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观察中度和重度牙周炎23例,男9例,女14例,年龄25～57岁。根据不同疗法分4组,第1组8例,施行骨、龈成形手术并在骨膜下植入胚胎骨,随后做修复矫形治疗。第2组6例,手术和第1组相同,但未做修复矫形治疗。第3组5例,施行龈成形手术,不植骨,随后做修复矫形治疗。第4组4例,做龈成形手术,不植骨,也未做矫形治疗。随诊10年,除进行临床检查以外,检查局部免疫指标——测定龈液和混合唾液的溶菌酶浓度,对照组为10名健康人。
23 cases of moderate and severe periodontitis were observed, including 9 males and 14 females, aged from 25 to 57 years. According to the different therapy divided into 4 groups, the first group of 8 cases, the implementation of bone and gingival surgery and periosteal implantation of embryonic bone, followed by repair orthopedic treatment. The second group of 6 cases, the same operation and the first group, but did not make orthopedic repair. Group 3 in 5 cases, the implementation of gingival surgery, no bone graft, followed by repair orthopedic treatment. The fourth group of 4 cases, do gingival surgery, no bone graft, nor orthopedic treatment. Follow-up for 10 years, in addition to clinical examination, check the local immune indicators - determination of gingival fluid and mixed saliva lysozyme concentration, the control group of 10 healthy people.