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苯并咪唑可能是最有希望的驱虫药,这类药物对所有常见的肠道线虫成虫均有治疗作用,但对幼虫的治疗作用尚未明确。一般来说,这类药物水溶性较低,口服后血液药物浓度也低。然而口服不同的咪唑类药物后,其血液浓度有显著不同。其中,丙硫咪唑血浓度最高,以单剂治疗常见肠道蠕虫病有很好疗效,在动物实验中有杀幼虫作用,所以丙硫咪唑可能是一种治疗人体寄生虫幼虫的有希望药物。本文研究的目的是观察单剂400亳克丙硫咪唑
Benzimidazoles are probably the most promising anthelmintics. These drugs have a therapeutic effect on all common intestinal nematode adults, but the therapeutic effect on larvae is not yet known. In general, these drugs are less water soluble and have lower blood drug concentrations after oral administration. However, oral administration of different imidazoles showed significant differences in blood levels. Among them, the highest concentration of albendazole blood concentration, a single treatment of common intestinal helminth disease has a good effect, killing larvae in animal experiments, so albendazole may be a hope for the treatment of human parasites larvae drugs. The purpose of this study is to observe a single dose of 400 mg of albendazole