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目的了解北京市肠道门诊腹泻患者中诺如病毒检出率的时间分布特征,为诺如病毒胃肠炎的防控提供依据。方法采用集中度与圆形分布法对北京市2011-2016年肠道门诊腹泻患者中诺如病毒检出率的时间分布特征进行分析,并结合北京市病原学检测结果判断新变异株的出现对诺如病毒检出率的影响。结果2011-2016年诺如病毒检出率集中度M=0.179。圆形分布分析结果为:高峰日在1月25日,高峰期为10月10日至次年5月12日。在新变异株出现的年度,诺如病毒检出率较高,集中度M>0.29,检出率高峰期小于6个月。而在没有新变异株出现的年度,诺如病毒检出率较低,集中度M<0.17,检出率高峰期大于7个月。结论冬春季北京市肠道门诊腹泻患者中诺如病毒检出率较高。新变异株出现的年份诺如病毒检出率的季节性更加明显。
Objective To understand the temporal distribution of Norovirus detection in patients with diarrhea in Beijing gut outpatient clinics and to provide a basis for prevention and control of Norovirus gastroenteritis. Methods The concentration distribution and circular distribution method were used to analyze the time distribution of norovirus detection rate in diarrhea patients during 2011-2016 in Beijing, and to determine the presence of new variant strains in Beijing based on the etiological test results The impact of Norovirus detection rate. Results The detection rate of Norovirus in 2011-2016 was M = 0.179. The circular distribution analysis results are as follows: The peak day is on January 25 and the peak season is October 10 to May 12. In the year when the new mutant appeared, the detection rate of Norovirus was higher, the concentration was M> 0.29, and the detection rate was less than 6 months. In the absence of new variants of the emergence of the year, norovirus detection rate is low, the concentration of M <0.17, the detection rate of more than 7 months. Conclusion The detection rate of Norovirus in patients with diarrhea in Beijing outpatient clinics in winter and spring is higher. The emergence of new strains of norovirus genotypes appear more seasonal in the year.