关于测定硫氧嘧啶及其同类药物的許多方法,早已載在药典及其他文献,但大部份得不到滿意的結果。較为滿意者,如英国药典1948年及1953年版所採用的方法,系加入过量的硝酸銀在硫氧嘧啶类的药物中,釋离出一定量的硝酸,用标准的鹼液来滴定釋出的硝酸。惟其結果往往偏低1%左右,故英国药典用校正后的当量来代替其实当量。若用上法测定硫氧嘧啶 Many methods for the determination of thiouracil and its analogs have long been included in the pharmacopoeias and other literature, but most have not been satisfactorily successful. More satisfied, as the method used in the 1948 and 1953 editions of the British Pharmacopoeia, was to add an excess of silver nitrate to a sulfathiazide drug to release a certain amount of nitric acid and to titrate with standard alkalis Nitric acid. However, the results are often low about 1%, so the British Pharmacopoeia with the corrected equivalent instead of actually equivalent. If using the method of determination of thiouracil