脑卒中是导致人类死亡的主要病因之一,预防脑卒中能降低死亡率和发病率,而对已明确的脑卒中危险因素的预防显得至关重要。传统的心脑血管病危险因素如年龄、高血压、脂质失调、糖尿病和吸烟等都与脑卒中的发生及再发有关,但这些并不能完全解释脑卒中事件的所有原因[1]。越来越多的流行病学研究表明同型半胱氨酸(homocysteine,Hcy)是脑卒中的危险因素,Hcy升高与脑卒中再发和全因死亡率风险增 Stroke is one of the leading causes of death in humans. Prevention of stroke can reduce mortality and morbidity, and prevention of the identified risk factors for stroke is crucial. Traditional cardiovascular and cerebrovascular disease risk factors such as age, hypertension, lipid disorders, diabetes and smoking are all related to the occurrence and recurrence of stroke, but these do not fully explain all the causes of stroke [1]. More and more epidemiological studies have shown that homocysteine ​​(Hcy) is a risk factor for stroke, increased Hcy and increased risk of recurrent stroke and all-cause mortality