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患者男性,18岁,学生,山东省曹县人。于1984年9月13日,因预防疟疾,服乙胺嘧啶50mg,连服2日,伯氨喹啉30mg,连服3天。第一日首次服药后两小时,觉头痛、无力。次晨发现鼻内有血痂,头痛头晕加重,下午卧床不起,傍晚内服扑热息痛0.5g。第三日鼻腔出血和发热,乃于9月18日入院。体检:体温38.3℃,贫血貌,全身皮肤粘膜未见出血点,余正常。血象:血红蛋白9克,白细胞1000/mm~3,中性14％,淋巴83％,单核3％,血小板8万,网织红细胞0.3％。骨髓象:有核细胞增
Male patient, 18 years old, student, Cao County, Shandong Province. On September 13, 1984, due to malaria prevention, taking pyrimethamine 50mg, and even served on the 2nd, primaquine 30mg, even for 3 days. Two hours after the first dose on the first day, headache, weakness. The next morning found that the nose with blood scab, headache, dizziness, bedridden in the afternoon, evening paracetamol 0.5g. Nasal bleeding and fever on the third day were admitted on September 18. Physical examination: body temperature 38.3 ℃, anemia appearance, systemic skin and mucous membrane no bleeding, more than normal. Blood: 9 grams of hemoglobin, leukocyte 1000 / mm ~ 3, 14% neutral, lymphatic 83%, mononuclear 3%, platelet 80,000, reticulocyte 0.3%. Bone marrow: nucleated cells increased