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Alzheimer氏于1907年首先描述了本病。Alzheimer氏病又名早老性痴呆、老年前期痴呆、弥漫性大脑萎缩症,是一种病理性衰老,临床表现为慢性进行性精神衰退。病因尚不清楚,可能为多因性,遗传因素有一定作用,而感染、中毒、消耗性躯体疾患及精神因素均可成为本病的诱发因素。新近的研究提示与某种慢病毒感染或周围环境中铝浓度过高有关。病理变化为弥漫性大脑皮层萎缩。国外有关此病的报道和研究甚多,国内文献报告较少,1960年刘氏报告过4例。现将我科1975年以来收治的经气脑造影证实的5例报告如下。
Alzheimer’s first described this disease in 1907. Alzheimer’s disease, also known as Alzheimer’s disease, senile dementia, diffuse brain atrophy, is a pathological aging clinical manifestations of chronic progressive mental decline. Etiology is not yet clear, may be due to multiple, genetic factors have a role, and infection, poisoning, consumption of physical disorders and mental factors can become a predisposing factor in this disease. Recent research suggests that it is associated with a lentivirus infection or excessive aluminum concentration in the surrounding environment. Pathological changes of diffuse cerebral cortical atrophy. There are many reports and studies abroad about the disease, few reports in domestic literature, and in 1960, Liu reported 4 cases. Now our department since 1975 admitted by pneumo-angiography report of 5 cases are as follows.