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铁-卟啉体系是生物体内众多重要氧化还原酶的活性中心。卟啉体系属于一种大环共轭配体结构,其与铁原子结合即可形成铁-卟啉体系,由于卟啉体系与铁原子配位情况较小,使得其分子配合物较为复杂。通过对该体系氧化还原反应机理的深入研究得知在整个反应过程中会出现许多带有正电荷或者自由基的铁氧复合物中间体,这些中间体的空间构造很复杂,传统的价键理论等很难作出合理的解释。基于此,开展对铁-卟啉氧化还原酶体系机构与氧化还原机理的研究,以为生物有机化学等学科的教学与科研提供一定的借鉴。
The iron-porphyrin system is the active center of many important oxidoreductases in the body. The porphyrin system belongs to a macrocyclic conjugated ligand structure, which can form an iron-porphyrin system by combining with an iron atom. Due to the coordination between the porphyrin system and an iron atom is small, its molecular complex is complicated. Through in-depth study on the redox reaction mechanism of the system, it is found that during the whole reaction many intermediate compounds of iron oxide complex with positive charges or free radicals appear. The structure of these intermediates is very complicated. The traditional theory of valence bond It is difficult to make a reasonable explanation. Based on this, the research on the mechanism of iron-porphyrin oxidoreductase system and redox mechanism is carried out to provide some reference for the teaching and research of bioorganic chemistry and other disciplines.