亚硝胺是一大类广谱强致癌物。流行病学调查早已提示亚硝胺与人类肿瘤的发生可能有密切关系,例如食管癌、胃癌、鼻咽癌等。迄今为止已发现的亚硝胺有100多种,其中75％左右可以诱发动物不同器官的肿瘤。 亚硝胺及其合成的前体物(亚硝酸盐及胺类),可以在食物和环境中存在。尤其是一些特殊加工的食物中亚硝胺的含量较高,如烟熏的或盐酶的鱼及肉中 Nitrosamines are a large class of broad-spectrum strong carcinogens. Epidemiological investigations have long suggested that nitrosamines may be closely related to the occurrence of human tumors, such as esophageal cancer, gastric cancer, and nasopharyngeal cancer. So far, more than 100 nitrosamines have been discovered, about 75% of which can induce tumors in different organs of animals. Nitrosamines and their synthetic precursors (nitrites and amines) can exist in food and in the environment. Especially in some specially processed foods, the content of nitrosamines is high, such as smoked or salt enzymes in fish and meat.