孕前肥胖和孕期增重过多是许多不良妊娠结局的重要危险因素,包括妊娠期糖尿病(gestational dia-betes mellitus,GDM)、妊娠期高血压疾病、早产和巨大儿等[1,2]。研究显示,孕期增重是可调控危险因素,即早期的膳食和行为干预可降低妊娠晚期不良妊娠结局的发生风险。因此,本研究拟探讨妊娠早期开始的强化生活方式干预对肥胖孕妇孕期增重和妊娠结局的影响,报告如下。 Pre-pregnancy obesity and excessive weight gain during pregnancy are important risk factors for many adverse pregnancy outcomes, including gestational diabetics mellitus (GDM), gestational hypertension, preterm labor and macrosomia [1,2]. Studies have shown that weight gain during pregnancy is a manageable risk factor that early intervention in diet and behavior can reduce the risk of adverse pregnancy outcome in late pregnancy. Therefore, this study intends to explore the impact of intensive lifestyle interventions on the weight gain and pregnancy outcome of obese pregnant women during the first trimester of pregnancy, the report is as follows.