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目的了解口腔专科医院住院患者多重药耐药菌(MDROs)的定植及感染情况,为临床合理使用抗菌药物提供依据。方法采用细菌分离培养和药敏试验方法,对某口腔专科医院住院患者鼻咽部MDROs定植与感染情况进行调查。结果共筛查住院患者94例,鼻腔定植耐甲氧西林金黄色葡萄球菌(MRSA)的检出率为3.2%,伤口分泌物MRSA的检出率为1.4%,产β-内酰胺酶(ESBLs)大肠埃希菌和肺炎克雷伯菌的检出率为2.7%。结论住院患者MRSA、ESBLs大肠埃希菌和肺炎克雷伯菌主动筛查检出率较低,采取主动筛查降低MDROs医院感染的效果需要进一步评估。
Objective To understand the colonization and infection of multidrug-resistant bacteria (MDROs) in hospitalized patients in oral specialty hospitals and provide the basis for rational use of antimicrobial agents in clinic. Methods The isolation and culture of MDROs in nasopharynx of hospitalized patients in a dental specialty hospital were investigated by bacterial isolation and culture and drug sensitivity test. Results A total of 94 inpatients were enrolled. The detection rate of methicillin-resistant Staphylococcus aureus (MRSA) in nasal cavity was 3.2% and the detection rate of MRSA in wound secretions was 1.4%. The production of β-lactamases (ESBLs) ) The detection rate of Escherichia coli and Klebsiella pneumoniae was 2.7%. Conclusions The detection rate of active screening of MRSA, ESBLs-producing Escherichia coli and Klebsiella pneumoniae in hospitalized patients is low, and the effect of active screening to reduce MDROs nosocomial infection needs further evaluation.