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1993年1月～1994年12月378例住院烧伤病人作创面细菌生态学调查,与70年代初和80年代中期所作的调查作比较。结果表明金葡菌三个时期占烧伤创面细菌检出率22.37%～26.62%,各时期间无显著性差异。铜绿假单胞菌90年代虽较70年代初显著下降(P<0.01),但较80年代中期显著上升(P<0.01)。而肠杆菌科细菌较80年代中期显著下降,呈现铜绿假单胞菌上升,肠肝菌科细菌下降的模式。这可能与铜绿假单胞菌对磺胺嘧啶银产生一定程度耐药和对肠杆菌科细菌敏感的亚胺配能作为首选抗生素有关。耐甲氧西林金葡菌(MRSA)占金葡菌的83.04%,而80年代中期为73.04%,呈上升趋势。应用敏感的去甲基万古霉素并不能减少 MRSA 在金葡菌中的比例。
From January 1993 to December 1994 378 cases of hospitalized burns patients were investigated for bacterial ecology and compared with the surveys conducted in the early 1970s and the mid 1980s. The results showed that Staphylococcus aureus bacteria accounted for 22.37% ~ 26.62% of the total number of burn wounds in the three periods, with no significant difference between different periods. Pseudomonas aeruginosa in the 1990s was significantly lower than that in the early 1970s (P <0.01), but significantly increased compared with the mid-1980s (P <0.01). The Enterobacteriaceae bacteria than the mid-80s significantly decreased, showing the rise of Pseudomonas aeruginosa, Enterobacteriaceae bacterial decline pattern. This may be related to Pseudomonas aeruginosa silver sulfadiazine to produce a degree of resistance and Enterobacteriaceae sensitive to the imine ligand as the first choice of antibiotics. Methicillin-resistant Staphylococcus aureus (MRSA) accounted for 83.04% of Staphylococcus aureus, compared with 73.04% in the mid-1980s, showing an upward trend. The use of sensitive nor-vancomycin did not reduce the proportion of MRSA in S. aureus.