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[背景]观察口服双歧四联活菌片对小儿抗生素相关性腹泻的预防作用.[病例报告]选择住院小儿肺炎患儿200例,随机分为2个组,即预防性应用双歧四联活菌片组(治疗组)及对照组,每组各为100例,观察抗生素相关性腹泻发生率及严重程度.对照组100例中发生腹泻为35例(35%),其中重度腹泻为10例,轻度腹泻为25例;治疗组100例中4例(4%)发生腹泻,均为轻度腹泻;治疗组腹泻发生率明显低于对照组(P<0.01).[讨论]口服双歧四联活菌片可预防小儿抗生素相关性腹泻的发生,疗效及依从性均较好.
[Background] To observe the preventive effect of oral live bifidobacterium on antibiotic-associated diarrhea in children. [Case Report] 200 children with hospitalized children with pneumonia were selected and randomly divided into two groups, namely, prophylactic use of bifidus quadruple (Control group) and control group (100 cases in each group), the incidence and the severity of antibiotic-associated diarrhea were observed.The incidence of diarrhea in 35 cases (35%) was 100 cases in the control group, of which severe diarrhea was 10 Cases, mild diarrhea was 25 cases; 4 cases (4%) of the 100 cases in the treatment group had diarrhea with mild diarrhea; the incidence of diarrhea in the treatment group was significantly lower than that in the control group [P <0.01] Quaternary live bacteria can prevent pediatric antibiotic-related diarrhea, efficacy and compliance are better.