患者男 ,5 5岁。主因对称性多关节肿痛 10余年 ,间断头晕、双下肢麻木 3个月 ,间断胸憋 1个月于 2 0 0 4年 1月2 4日入院。患者 1987年外伤后出现双踝关节肿痛 ,并逐渐累及双腕、双手多个掌指关节及近端指间关节 ,未予诊治。1990年始 ,上述症状加重 ,出现双腕、双手多个掌指关 Patient male, 5 5 years old. Symptoms of multiple joint pain due to symmetry more than 10 years, intermittent dizziness, numbness of lower extremities 3 months, intermittent chest simmer for 1 month on January 24, 2004 admission. Patients with bilateral ankle joint swelling and pain after the trauma in 1987, and gradually involving both wrists, hands and more of the metacarpophalangeal and proximal interphalangeal joints, no diagnosis and treatment. Beginning of 1990, the above symptoms worsened, appeared wrist, hands and more palms off