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乙醇是诱发心肌疾病的重要原因。在美国乙醇引起的心肌疾病患者多达二十余万人,占城市医院确诊为心肌病的3%。其表现包括心肌甘油三酸酯聚积、脂肪酸β氧化作用降低、高度房性和室性心律失常、充血性心功能不全,甚至有维生素缺乏。近来,本文作者鉴定了从实验动物心脏提取的乙醇代谢产物及其产生的脂肪酸乙酯的特性,并将心脏直接暴露于乙醇进行了心肌活组织检查分析,首次做了人体心脏中乙醇代谢产物的鉴
Ethanol is an important cause of heart disease. In the United States caused by ethanol-induced cardiomyopathy patients as many as 200,000 people, accounting for the city hospital diagnosed cardiomyopathy 3%. Its manifestations include myocardial triglyceride accumulation, decreased fatty acid beta oxidation, atrial and ventricular arrhythmias, congestive heart failure, and even vitamin deficiency. Recently, the authors identified the ethanol metabolites extracted from the heart of experimental animals and the characteristics of their fatty acid ethyl esters. The heart was exposed directly to ethanol for myocardial biopsy analysis. For the first time, the ethanol metabolites of the human heart Kam