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碱性磷酸酶(AKP)广泛分布于人体各组织器官中,以骨、肝、肠粘膜中最丰富。AKP主要由骨细胞产生,经肝随胆汁入肠,成人正常值为2～4布氏单位或3～13金氏单位。测定血清AKP的活性,可以辅助诊断上述器官的疾病。 1.肝胆疾患时,血清AKP总活性升高,但疾病性质不同,升高的程度也不同。在阻塞性黄疸、胆汁性肝硬化、胆小管性肝炎时,AKP显著升高,常在10布氏单位以上;在肝细胞性黄疸仅轻度升高,
Alkaline phosphatase (AKP) is widely distributed in various tissues and organs of the human body, with the most abundant in bone, liver and intestinal mucosa. AKP is mainly produced by bone cells, the liver with bile into the intestine, adult normal for 2 to 4 units of Brinell or 3 to 13 units of gold. Determination of serum AKP activity, can help diagnose the disease of the above organs. 1. Hepatobiliary disease, serum total AKP activity increased, but the disease is different, the degree of increase is also different. In obstructive jaundice, biliary cirrhosis, cholecystitis, AKP was significantly elevated, often more than 10 Brinell units; only mildly increased in hepatocellular jaundice,