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目的:观察热毒宁注射液联合锌剂治疗小儿手足口病的疗效。方法:将100例手足口病患儿随机分为治疗组和对照组各50例,对照组予热毒宁注射液治疗,治疗组在对照组治疗的基础上给予硫酸锌糖浆治疗。两组疗程均为7d,观察两组症状、体征的改善情况。结果:治疗组总有效率为98.0%,优于对照组的84.0%(P<0.05);治疗组热退时间、疱疹愈合时间、口腔疼痛减轻时间及总病程均短于对照组(P<0.05)。结论:热毒宁注射液联合锌剂治疗小儿手足口病可有效改善患者临床症状、体征,减少并发症,缩短病程,且无明显不良反应,值得临床推广应用。
Objective: To observe the therapeutic effect of Renduining injection combined with zinc agent in the treatment of hand-foot-mouth disease in children. Methods: 100 cases of hand, foot and mouth disease were randomly divided into treatment group and control group, 50 cases in each group. The control group was treated with Renduining injection. The treatment group was treated with zinc sulfate syrup on the basis of the control group. The two courses of treatment were 7d, observation of two groups of symptoms and signs of improvement. Results: The total effective rate of the treatment group was 98.0%, which was significantly better than that of the control group (84.0%, P <0.05). The thermal back-up time, herpes healing time, oral pain relief time and total duration of the treatment group were shorter than those of the control group ). Conclusion: The combination of RT - injection and zinc agent in children with HFMD can effectively improve the clinical symptoms and signs of patients, reduce complications, shorten the course of the disease, and no obvious adverse reactions, worthy of clinical application.