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目的探讨女性生殖道支原体和脲支原体感染的现状及对抗菌药物的耐药性,为临床医师合理使用抗菌药物提供科学依据。方法对766例女性生殖道感染患者进行支原体和脲支原体培养及药敏检测。结果 766例患者检出支原体和脲支原体阳性448例,阳性率为58.49%,其中解脲脲支原体(Uu)阳性率为44.65%,人支原体(Mh)为2.61%,解脲脲支原体和人支原体混合感染率为11.23%;支原体和脲支原体感染以中青年为主,占阳性患者的75.89%,12种常用抗菌药物中米诺环素、多西环素和甲砜霉素耐药率最低,对红霉素、阿奇霉素、左氧氟沙星、环丙沙星耐药率最高。结论女性生殖道炎症患者中Uu感染率最高,治疗支原体和脲支原体感染应根据药敏结果合理使用抗菌药物。
Objective To investigate the prevalence of mycoplasma and ureaplasma urealyticum in female genital tract and its resistance to antibacterial drugs, and to provide scientific basis for rational use of antibacterial drugs by clinicians. Methods A total of 766 female genital tract infections were tested for mycoplasma and ureaplasma urealyticum. Results The positive rate of mycoplasma and ureaplasma was 58.49% in 766 cases, of which the positive rate of Uu was 44.65% and that of human mycoplasma was 2.61%. UU and Mycoplasma hominis The mixed infection rate was 11.23%. Mycoplasma and Ureaplasma urealyticum infection were mainly middle-aged and young, accounting for 75.89% of the positive patients. Minocycline, doxycycline and thiamphenicol were the lowest among 12 commonly used antibiotics, The highest rates of erythromycin, azithromycin, levofloxacin, ciprofloxacin resistance. Conclusion Uu infection rate is the highest in women with genital tract inflammation. The treatment of mycoplasma and ureaplasma urealyticum should be based on the drug susceptibility results rational use of antimicrobial agents.