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目的比较经肺热稀释法和肺动脉导管法测量血流动力学参数。方法通过经肺热稀释法(COa)、右心漂浮导管热稀释法(COpa)和脉搏指示连续心排出量测量法(COpc)在20只犬感染性休克模型制作前后以及应用不同液体容量复苏后测量心输出量和血液动力学参数,比较COa、COpa、COpc之间的关系。并且比较经肺热稀释法、右心漂浮导管热稀释法两种方法测得的血液动力学参数(包括SVRI和SVI)。结果实验全程中COpc、COa和COpc的相关性好,准确性很稳定。体循环指数(SVRI)和每搏输出量指数(SVI)在经肺热稀释法和右心漂浮导管热稀释法比较中呈正相关。结论在犬感染性休克模型中,我们发现与肺动脉导管法相比较,经肺热稀释法测量得到的血流动力学参数准确稳定,COpc准确、可靠,体循环指数(SVRI)和每搏输出量(SVI)在两种方法中的相关性良好。
Objective To compare the hemodynamic parameters measured by pulmonary thermodilution and pulmonary catheterization. Methods COa, COpa, and COpc were measured before and after 20 septic shock models were established and after resuscitation with different fluid volumes Cardiac output and hemodynamic parameters were measured and the relationship between COa, COpa and COpc was compared. The haemodynamic parameters (including SVRI and SVI) measured by both methods of pulmonary thermodilution and right-heart catheterization were compared. Results The correlation between COpc, COa and COpc was good and the accuracy was stable throughout the experiment. SVRI and stroke volume index (SVI) were positively correlated in the comparison between HAM and right ventricular catheter thermal dilution. Conclusions In the dog model of septic shock, we found that hemodynamic parameters measured by the pulmonary thermodilution method were accurate and reliable, with accurate and reliable COpc, volume index of systemic circulation (SVRI) and stroke volume per output (SVI The correlation between the two methods is good.