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本文探讨成人特发性血小板减少性紫癜(ITP)患者用7S-丙种球蛋白制剂治疗的效果,及其对血小板相关免疫球蛋白G(PAIgG)和血小板功能的影响。本组18例,其中男7、女11例,年龄18～74岁。急性ITP 2例;慢性ITP16例,其中4例已行脾切除术。全部患者均给予免疫球蛋白0.4g/kg静脉注射,连用5天为1个疗程,其中6例使用过2个疗程。如以血小板数升高至少为治疗前的两倍,总数不少于5万/mm~3为治疗有效,则2例急性ITP中有1例、12例慢性ITP未行脾切除者中有7例、4例慢性ITP已行脾切除者全部治疗有效。于治疗后第4～5天血小板数达到峰值。1例急性ITP完全缓解;慢性型的疗效是暂时的,持续18～25天。5例接
This article investigates the effect of 7S-gamma globulin in patients with adult idiopathic thrombocytopenic purpura (ITP) and its effect on platelet-associated immunoglobulin G (PAIgG) and platelet function. The group of 18 patients, including 7 males and 11 females, aged 18 to 74 years. 2 cases of acute ITP; 16 cases of chronic ITP, of which 4 cases had splenectomy. All patients were given immunoglobulin 0.4g / kg intravenously, once every 5 days for a course of treatment, of which 6 cases used two courses. If the increase in platelet number at least twice before treatment, the total number of not less than 50000 / mm ~ 3 for the treatment of effective, then 2 cases of acute ITP in 1 case, 12 cases of chronic ITP splenectomy were 7 Cases, 4 cases of chronic ITP splenectomy were all effective. The platelets reached its peak on the 4th to 5th days after treatment. 1 case of acute ITP complete remission; chronic type of effect is temporary, lasting 18 to 25 days. 5 cases connected