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目的 探讨广西壮、汉族妇女骨密度 (bonemineraldensity ,BMD)和绝经后壮、汉族妇女骨质疏松 (osteoporosis,OP)发生率是否存在差异性 ,为骨质疏松防治提供依据。方法 居住南宁 1 0年以上的健康绝经前妇女 1 79名 ,绝经后妇女 1 6 3名 ,记录其祖父母、外祖父母的民族 ,祖父母和外祖父母均为同一民族 (汉族或壮族 )者纳入本研究。同时记录受试者的年龄、初潮年龄、绝经年限 (绝经后妇女 )、孕次、产次。受试前 3个月内至少有 1次月经来潮者纳入绝经前妇女组 ;绝经 1年或以上者纳入绝经后妇女组。测量身高、体重 ,计算体重指数 (BMI)。用法国DMS公司的DEXA检测受试者腰椎 (L2 ～L4)正位、左髋部(股骨颈、Word s三角、大转子 )、左前臂 (超远端、远端 )的BMD ,并进行比较。结果 绝经前壮族妇女除股骨颈、前臂BMD略高于 (0 93%～ 1 4 4 % )或等于汉族妇女外 ,其余检测部位的BMD均低于汉族妇女 (0 92 %～ 5 92 % ) ,其中L2 ～L4的BMD分别较汉族妇女低 4 92 % (P =0 0 6 7)、5 2 6 % (P =0 0 5 4 )、5 92 % (P =0 0 37) ;相反 ,绝经后壮族妇女除L2 和前臂超远端的BMD略低于 (0 1 5 %～ 0 99% )汉族妇女外 ,其余部位的BMD均高于 (0 1 3%～ 2 79% )汉族妇女 ,虽然差异无统计学意义 (P >0 0 5
Objective To investigate the differences of bone mineral density (BMD) and osteoporosis (OP) between Zhuang and Han nationality women in Zhuang and Han nationalities in Guangxi and provide basis for prevention and treatment of osteoporosis. Methods A total of 1 79 healthy pre-menopausal women and 1 6 3 post-menopausal women who lived in Nanning for more than 10 years were enrolled in the study. All the nationalities, grandparents and grandparents who recorded their grandparents were from the same ethnic group (Han or Zhuang) . The subjects’ age, menarche age, menopause (postmenopausal women), pregnancy time and delivery time were also recorded. At least 1 menstrual period was included in the premenopausal women during the 3 months before the test. Menopausal women who were at least one year old were included in the postmenopausal women group. Height, weight, body mass index (BMI) were calculated. The BMD of lumbar vertebrae (L2 ~ L4), left hip (femoral neck, Word s triangle, greater trochanter) and left forearm (distal and distal) were measured by DEXA of DMS of France. . Results In premenopausal Zhuang women, the mean BMD of femoral neck and forearm was slightly higher than that of Han females (0 93% -1 144%) or equal to that of Han nationality women. The BMDs of the other sites were lower than those of Han women (0 92% -5 92%), Among them, the BMD of L2 ~ L4 were respectively lower than 92% (P = 0 067), 526% (P = 0 054) and 5 92% (P = 0 037) in Han women. On the contrary, The post-Zhuang women had higher BMD than Han women (0 1 3% -2 79%) except L2 and forearm distal BMD (0 1 5% ~ 0 99%) Han women The difference was not statistically significant (P> 0.05)