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目的探讨静脉溶栓治疗心肺复苏术后急性心肌梗死(AMI)的临床疗效。方法选取2012年1月—2015年1月成都市第二人民医院收治的成功行心肺复苏术的AMI患者83例,根据是否行静脉溶栓治疗分为对照组41例和治疗组42例。比较两组患者梗死血管再通率、出血发生率、心脏事件发生率及术后2周病死率。结果治疗组患者梗死血管再通率高于对照组,心脏事件发生率及术后2周病死率低于对照组(P<0.05);两组患者出血发生率比较,差异无统计学意义(P>0.05)。结论对心肺复苏术后AMI患者行积极的静脉溶栓治疗可提高患者梗死血管再通率,降低心脏事件发生率,进而提高患者救治成功率。
Objective To investigate the clinical efficacy of intravenous thrombolysis in the treatment of acute myocardial infarction (AMI) after cardiopulmonary resuscitation. Methods From January 2012 to January 2015, 83 patients with AMI undergoing successful cardiopulmonary resuscitation (CPR) in Chengdu Second People’s Hospital were divided into control group (n = 41) and treatment group (n = 42) according to whether they were treated with intravenous thrombolysis or not. The infarct revascularization rate, the incidence of bleeding, the incidence of cardiac events and the 2-week postoperative mortality rate were compared between the two groups. Results The recanalization rate of infarction in the treatment group was higher than that of the control group. The incidence of cardiac events and 2-week postoperative mortality were lower than those in the control group (P <0.05). There was no significant difference in the incidence of bleeding between the two groups (P > 0.05). Conclusions Positive venous thrombolysis in patients with AMI after cardiopulmonary resuscitation can improve the recanalization rate of infarction and reduce the incidence of cardiac events, thus improving the success rate of treatment.