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自身骨髓移植(ABMT)能够有效地提高急性白血病的长期存活率。近年来,我科在强烈诱导和巩固化疗的基础上,从1991年5月起已成功地进行了4例急性白血病的ABMT。现将有关情况报告如下。病例及方法一、病例资料:见表1。二、ABMT前的体内净化除例1外,其余3例在ABMT前1月内均接受了以中剂量阿糖胞苷为主的移植前强化治疗。剂量为1.0g/m~2/天,分2次静滴,疗程4天,在骨髓开始恢复时采集骨髓。三、骨髓的采集、保存和回输骨髓采集的时机为化疗后骨髓增生活跃时。在持续硬膜外麻醉下,从髂后上棘多部位穿刺采集骨髓,按2:1比例与肝素抗凝的
Autologous bone marrow transplantation (ABMT) can effectively improve the long-term survival of acute leukemia. In recent years, our department has successfully performed 4 cases of acute leukemia ABMT since May 1991 on the basis of intensive induction and consolidation of chemotherapy. The relevant information is as follows. Cases and methods First, the case information: See Table 1. Second, before the ABMT in vivo purification In addition to cases 1, the remaining three cases within 1 month prior to ABMT were received in the dose of cytarabine-based pre-transplant intensive treatment. Dose of 1.0g / m ~ 2 / day, intravenous infusion 2 times, the course of 4 days, bone marrow recovery began to collect bone marrow. Third, the collection of bone marrow, bone marrow collection and preservation of the return of the timing of bone marrow hyperplasia after chemotherapy when active. Under continuous epidural anesthesia, bone marrow was collected from multiple sites of the posterior superior iliac spine by a ratio of 2: 1 and heparin anticoagulation