门脉高压时静脉曲张出血是胃肠出血最常见的原因。因此,门脉高压的药物治疗目的,应是阻止和预防静脉曲张出血。理想的降门脉压药物应是有效率高,无禁忌症和副作用;应用简便,口服后吸收,并可长期应用;不通过肝代谢或胆道排泄(以免加重肝损伤)。而目前所用药物的情况是:副作用大,止血效果不甚满意,停药后再出血复发率高,不能提高总的生存率。故只能作为内科姑息疗 Variceal bleeding when portal hypertension is the most common cause of gastrointestinal bleeding. Therefore, the purpose of medical treatment of portal hypertension should be to prevent and prevent bleeding varicose veins. Ideal antihypertensive drugs should be high efficiency, no contraindications and side effects; easy to apply, after oral absorption, and long-term use; not through the liver metabolism or biliary excretion (so as not to aggravate liver damage). The current situation of the drug used are: side effects, hemostatic effect is not satisfied, re-bleeding after discontinuation of high recurrence rate, can not increase the overall survival rate. It can only be used as palliative medicine