后天梅毒主要通过性接触感染,已为众所周知,但一家三人同患梅毒尚属罕见。现就我们所见病例报道如下。例1:女,8岁(先证者)。因其母发现该患儿外阴、肛周赘生物2天来我所就诊。既往该患儿无外阴破溃史,病后局部无自觉症状。体检:一般情况良好,体重22ｋｇ,体温37℃,五官未见异常, Acquired syphilis is mainly known to have sexually transmitted infections and is well known, but it is still rare for a trio to develop syphilis. Now we have seen the case as follows. Example 1: Female, 8 years old (probationer). Because of her mother found the child’s vulva, perianal neoplasm 2 days to my clinic. In the past the patient had no history of vulvae ulceration, no local symptoms after the illness. Physical examination: generally good, weight 22kg, body temperature 37 ℃, facial features were normal,