肝脏有许多参与骨代谢的调节因子,这些因子对维生素贮存和分泌起重要作用。肝脏通过产生和分泌胆汁,影响维生素K、维生素D 和钙的吸收,同时在数种调钙素的代谢中也起作用,因此,慢性肝病、肝功不全患者可并发骨疾患。肝性骨营养不良是指在晚期慢性肝病或胆汁郁积性疾病并发的代谢性骨病,主要包括骨质疏松症 There are many liver regulators involved in bone metabolism, these factors play an important role in vitamin storage and secretion. The liver, through the production and secretion of bile, affects the absorption of vitamin K, vitamin D and calcium and also plays a role in the metabolism of several calcitonin, so patients with chronic liver disease and liver insufficiency may develop bone disease. Hepatic osteodystrophy refers to metabolic bone disease complicated by chronic liver disease or cholestatic disease in the late stage, including mainly osteoporosis