本文观察了100例恶性肿瘤患者血片及37例良性肿瘤、39例普通疾病、80例正常人血片中多形核、淋巴细胞等细胞核内“恶性肿瘤相关变化”(Maligancy Associated Changes MAC)。结果表明,有61％癌患者检出MAC,检出率在20％—83.3％。良性瘤、普通疾病和正 常人中,MAC检出率分别为5.4％、5.1％、3.7％。提示,当MAC>20％者预示身体某处有癌 生长的可能。此时应作临床观察。该方法简便易行,病人痛苦小,不失为一种恶性肿瘤的辅助 诊断指标。 In this paper, we observed the “malignancy-associated changes” in the nucleus of polymorphonuclear cells, lymphocytes, etc. in 100 malignant tumor patients and 37 benign tumors, 39 common diseases, and 80 normal human blood films. The results showed that 61% of cancer patients detected MAC, and the detection rate was 20%-83.3%. In benign tumors, common diseases, and normal people, the MAC detection rates were 5.4%, 5.1%, and 3.7%, respectively. Tip: When MAC > 20%, it indicates the possibility of cancer growth somewhere in the body. At this point clinical observations should be made. The method is simple and easy, and the patient has little pain. It is an auxiliary diagnostic indicator of malignant tumor.