用单克隆抗体、免疫组化方法(ABC)对10例人动脉粥样硬化(AS)病变中T淋巴细胞亚群进行分析。观察结果发现:早期病变中总T淋巴细胞多于晚期,但各期病变中抑制性淋巴细胞(Ts)皆明显多于辅助性T淋巴细胞(T_H),T_H/Ts分别为1:1.8和1:2.3,其比值分别为0.36和0.43。这一结果表明:在AS病变中,Tu/Ts比值是降低的,这一变化是否与AS发生、发展有关,本文对其进行初探。 T lymphocyte subsets in 10 human atherosclerotic lesions were analyzed by monoclonal antibody and immunohistochemistry (ABC). The results showed that there were more total T lymphocytes in early stage than in late stage, but the number of inhibitory lymphocytes (Ts) in each stage were significantly higher than that of helper T lymphocytes (T_H). The T_H / Ts were 1: 1.8 and 1 : 2.3, with ratios of 0.36 and 0.43, respectively. The results show that: in the AS lesions, Tu / Ts ratio is reduced, whether this change is related to the occurrence and development of AS, this article to explore.