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目的 :观察纳美芬对急性乙醇中毒患者治疗的临床疗效。方法 :从2014年1月-2015年1月我院急诊治疗的急性乙醇中毒患者随机分为观察组和对照组各25例,均给予基础治疗,观察组应用纳美芬,对照组应用纳洛酮,观察两组患者症状改善情况。结果观察组患者起效时间、症状缓解时间、症状消失时间均短于对照组,差异有统计学意义(P<0.05)。结论 :盐酸纳美芬可显著缩短急性乙醇中毒患者症状消失时间,且安全、稳定,值得在临床上推广。
Objective: To observe the efficacy of nalmefene in the treatment of patients with acute alcoholism. Methods: From January 2014 to January 2015, acute alcohol poisoning patients in our hospital were randomly divided into observation group and control group, 25 cases were given basic treatment, the observation group was treated with nalmefene, while the control group was treated with naloxone Ketone, observed two groups of patients to improve the symptoms. Results The onset time, symptom relief time and symptom disappearance time in the observation group were shorter than those in the control group, with significant difference (P <0.05). Conclusion: Nalmefene hydrochloride can shorten the time of symptom disappearance in patients with acute alcoholism, and it is safe and stable and worth to be popularized clinically.