Stout于1962年对一组具有上皮样圆形细胞的胃非上皮肿瘤命名为成平滑肌瘤,部分有恶变,1969年世界卫生组织称之为上皮样平滑肌瘤.鉴于免疫组织化学和电镜检查未能找到平滑肌现象,最好将此类肿瘤称之为上皮样胃基质肿瘤,并有良恶性之分.Mayo临床中心于1960～1986年曾收治477例胃基质肿瘤病人,其中55例为上皮样胃基质肿瘤,分析其临床和病理特点.全组55例中,男37例,女18例,平均年龄63岁(13～88岁),常见的症状有消化不良和疼痛(35%)、黑粪(9%)、扪及腹块(7%).1例出现肠梗阻,15例无症状(27%).18例在胃外尚有22个肿瘤.53%肿瘤位于胃体,33%位于胄窦,14%位于胃底、贲门部.肿瘤可向腔内或胃壁外生长,6例侵犯邻近器官.40例作了钡餐检查,26例发现异常,其中13例胃壁内肿瘤,1例有脐样外观,另1例有粘膜溃疡.5例有腔内息肉,5例有外在压迹.17例做了胃镜检查,12例有异常发现. Stout named a leiomyoma in a group of gastric non-epithelial neoplasia with epithelium-like round cells in 1962. Some of them had malignant transformation. In 1969 the WHO called epithelioid leiomyoma. In view of immunohistochemistry and electron microscopy Failure to find a smooth muscle phenomenon is best referred to as epithelioid-like gastric stromal tumors, with distinctions between benign and malignant. The Mayo Clinic Center had 477 patients with gastric stromal tumors from 1960 to 1986, of which 55 were epithelial Gastric stromal tumors were analyzed for clinical and pathological features. Of the 55 patients in the entire group, 37 were males and 18 were females. The average age was 63 years (13 to 88 years). Common symptoms were dyspepsia and pain (35%). Intestinal obstruction occurred in 1 case of black feces (9%), hernia and abdominal mass (7%), 15 cases were asymptomatic (27%). 18 cases had 22 tumors outside the stomach. 53% of the tumors were located in the stomach, 33 % is located in the orbital sinus, 14% in the fundus, cardia. The tumor can grow in the cavity or outside the stomach wall, 6 cases of adjacent organs. 40 cases of barium meal examination, 26 cases were found abnormal, of which 13 cases of intramural tumors, 1 For example, there was an umbilical appearance, the other had mucosal ulcers, 5 had polyps in the cavity, 5 had external pressure traces, 17 had gastroscopy, and 12 had abnormal findings.