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原发性肾病综合征(INS)的患儿多合并变态反应性疾病,血清IgE值(以下称IgE值)经常呈高值。对象和方法1978～1990年在新泻吉田医院长期住院的INS患儿中,用放射免疫测定法每月一次测定IgE值,本次以满6岁的79例为对象追踪IgE值1年以上。初发年龄2.2～16.4岁,未满10岁75例,占94%,男60例,女19例,男女之比为3.2:1.观察的期间(满6岁后的住院期间)1年～9.9年(平均3.3±2.2年)。观察开始的年龄为6～17.1岁,观察结束年龄为7～19.4岁。合并变态反应性疾病17例(22%)。
Children with primary nephrotic syndrome (INS) are often associated with allergic disease, and serum IgE values (hereinafter referred to as IgE values) are often high. Subjects and Methods IgE values were measured monthly by radioimmunoassay in patients with long-term hospitalizations at Yoshida Hospital in Niigata from 1978 to 1990. The IgE level was tracked for over 1 year in 79 infants aged 6 years. Initial onset age of 2.2 ~ 16.4 years old, under the age of 10 75 cases, accounting for 94%, 60 males and 19 females, the ratio of men to women was 3.2: 1. Observation period (6 years of age after hospitalization) 1 year ~ Nine-nine years (an average of 3.3 ± 2.2 years). Observation of the beginning of the age of 6 to 17.1 years old, observation of the end of the age of 7 to 19.4 years. Allergic diseases in 17 cases (22%).