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采用比色法对６１例喉鳞状细胞癌、２５例喉及颈部良性病变患者和４０例正常人的血清唾液酸（ＳＡ）含量进行测定。结果表明，喉癌患者血清ＳＡ含量高于良性病变患者和正常人，差异有极显著性意义（Ｐ＜０．０１）。以大于正常人血清ＳＡ含量的＋２ｓ为阳性，喉癌患者血清ＳＡ阳性率为６７．５％，良性疾病患者阳性率为１６．０％，差异有极显著性意义（Ｐ＜０．０１）。此外，血清ＳＡ含量与喉癌患者的临床分期及预后密切相关。提示血清ＳＡ测定是喉癌辅助诊断、病情估计和疗效观察的一种有价值的手段。
The contents of sialic acid (SA) in 61 cases of laryngeal squamous cell carcinoma, 25 cases of benign lesions of the larynx and neck and 40 normal persons were determined by colorimetry. The results showed that the serum SA content in patients with laryngeal cancer was higher than that in benign patients and normal subjects, the difference was significant (P <0.01). The positive rate of serum SA was 67.5% in patients with laryngeal cancer and 16.0% in patients with benign diseases, the difference was statistically significant (P <0.01). In addition, serum SA levels are closely related to the clinical stage and prognosis of patients with laryngeal cancer. Tip serum SA determination of laryngeal cancer diagnosis, disease estimation and efficacy of a valuable tool.