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急性、严重的大量失血,可导致包括患者机体凝血障碍在内的严重病理生理紊乱。此时,需要对包括病因在内各种情况进行紧急处置,快速、合理地输注大量血液或血液制品往往对拯救生命起到关键作用。定义及病因大量出血一般指失血量占体液总量30%以上的急性失血。由此关联的大量输血,国际上有以下3种定义。1 24 h内输血量≥8~10 u红细胞(每单位以450 m L±10%)计,即接近或超过总血容量[1]。欧美
Acute, severe massive blood loss can result in severe pathophysiological disorders, including coagulation disorders in the patient’s body. At this point, the emergency management of various conditions, including the cause, needs to be urgently performed. Rapid and rational infusion of large quantities of blood or blood products often plays a key role in saving lives. Definition and causes A large number of bleeding generally refers to the amount of blood loss accounts for more than 30% of the total amount of body fluid acute blood loss. A large number of blood transfusions associated therewith internationally have the following three definitions. Blood transfusion volume ≥8-10 u red blood cells (450 m L ± 10% per unit) within 24 h, ie, approaching or exceeding total blood volume [1]. Europe and the United States