目的:本研究评价了在左心耳(LAA)放置装置预防房颤(AF)患者血栓栓塞性卒中的可行性。背景:荟萃分析证实,非风湿性AF患者的左房血栓事件中约有90%位于LAA。方法:WATCHMAN左心耳封闭系统是一种镍钛记忆合金装置,可经皮植入以封闭LAA。患者分别于第45天和6个月时进行临床随访和经食管超声心动图检查,此后每年随访1次。结果:66例患者放置了封闭系统。平均随访时间为740±341d。第45天时,根据试验方案,93%(54/58)的装置成功地封闭了LAA PURPOSE: This study evaluated the feasibility of prophylactic thromboembolic stroke in patients with atrial fibrillation (AF) in atrial appendage (LAA). Background: A meta-analysis confirms that approximately 90% of left atrial thromboembolic episodes in non-rheumatoid AF patients are located in LAA. METHODS: The WATCHMAN left atrial appendage closure system is a nickel-titanium memory alloy device that can be implanted percutaneously to seal off LAA. Patients were followed up and transesophageal echocardiography at day 45 and 6, respectively, and were followed up once a year thereafter. Results: Sixty-six patients had a closed system. The average follow-up time was 740 ± 341d. On day 45, 93% (54/58) of the devices successfully closed the LAA according to the protocol