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目的:观察氟康唑与克霉唑阴道栓联合用药对霉菌性阴道炎的治疗效果。方法:选取本院收治的霉菌性阴道炎患者72例,随机分为两组,各36例。对照组单纯应用克霉唑阴道栓治疗,观察组在此基础上配合氟康唑治疗,比较两组疗效。结果:观察组总有效率为93.75%明显高于对照组的84.38%;观察组复发率为6.25%明显低于对照组的21.88%;对比不良反应发生率,观察组为12.50%明显低于对照组的25.00%,由于P均<0.05,差异显著,有统计学意义。结论:氟康唑联合克霉唑阴道栓治疗霉菌性阴道炎的疗效确切,不易复发。
Objective: To observe the therapeutic effect of combination therapy of fluconazole and clotrimazole vaginal suppository on mycotic vaginitis. Methods: Seventy-two patients with mycotic vaginitis admitted to our hospital were randomly divided into two groups (36 in each). The control group was treated with clotrimazole vaginal suppository only. On the basis of this observation, the observation group was treated with fluconazole, and the curative effect was compared between the two groups. Results: The total effective rate was 93.75% in observation group and 84.38% in control group. The recurrence rate was 6.25% in observation group and 21.88% in control group. The incidence of adverse reactions in observation group was significantly lower than that in control group 25.00% of the group, P <0.05, the difference was significant, statistically significant. Conclusion: The effect of fluconazole combined with clotrimazole vaginal suppository in the treatment of fungal vaginitis is exact and not easy to relapse.