首次用高分子负载型双金属催化剂 PVP- Pd Cl2 - Cu Cl2 / PPh3体系催化 α- (6’-甲氧基 - 2’-萘基 )乙醇与一氧化碳及甲醇进行羰化反应制备萘普生甲酯 ,分别对温度、压力、时间、P/ Pd比等影响因素进行了考察 ,在反应条件为 10 0℃、 16～ 2 0 h、CO压力 4.0 MPa、P/ Pd=3时 ,转化率可达 97.4% ,异正比为 14.4.在同样条件下制备萘普生乙酯及萘普生异丙酯 ,转化率及选择性均有明显下降 .另外 ,该催化剂体系也可催化其它类型 α-芳基乙醇的羰化反应 . The first use of polymer supported bimetallic catalyst PVP-Pd Cl2 - Cu Cl2 / PPh3 system catalyzed α- (6’-methoxy - 2’-naphthyl) ethanol and carbon monoxide and methanol for carbonylation reaction naproxen The effects of temperature, pressure, time, P / Pd ratio and other factors were investigated. Under the conditions of 10 0 ℃, 16 ~ 20 h, CO pressure 4.0 MPa and P / Pd = 3, Up to 97.4%, the direct ratio of 14.4. Under the same conditions, preparation of ethyl naproxen and naproxen isopropyl, conversion and selectivity were significantly reduced. In addition, the catalyst system can also catalyze the other types of α-a Carbonylation of ethanols.