CYCLASE相关论文
The effects of nitric oxide (NO) on electroretinograms and light responses of horizontal cells intra-cellularly recorde......
For further clarifying the central mechanism for penile erec-tion, the effect of metheylene blue on oxytocin-induced pe......
Overexpression of the diguanylate cyclase CdgD blocks developmental transitions and antibiotic biosy
Cyclic dimeric GMP(c-di-GMP)has emerged as the nucleotide second messenger regulating both development and antibiotic pr......
环—磷酸腺苷(cAMP)和环—磷酸鸟苷(cGMP)是存在于同一机体内的不同的生理活性物质,cAMP/cG MP两者在细胞内起着对立统一的作用,......
Soluble guanylate cyclase(sGC) is a critical heme-containing enzyme involved in NO signaling.The dimerization of sGC sub......
VPAC1是垂体腺苷酸环化酶激活多肽(pituitary adenylate cyclase-activating polypeptide,PACAP)和血管活性肠肽(vasoactive intes......
Genes Related to Oxytocin and Arginine-Vasopressin Pathways:Associations with Autism Spectrum Disord
Autism spectrum disorder(ASD) is a highly heritable neurodevelopmental disorders characterized by impaired social intera......
Effects of pituitary adenylate cyclase activating polypeptide on CD4~+/CD8~+T cell levels after trau
BACKGROUND:The effect of pituitary adenylate cyclase activating polypeptide(PACAP)during traumatic brain injury(TBI) and......
Mobilization of intracellular Ca2+ stores is involved inmany diverse cell functions, including: cell proliferation;diffe......
ADP-ribosyl cyclase display an altered role in isoproterenol-induced cardiac hypertrophy in young an
AIM:To examine the potential role of ADP-ribosyl cyclase(ADPRclase)in the pathogenesis of isoproterenol(ISO)-induced car......
目的 从滇产毛喉鞘蕊花植物中提取到3个佛司可林类似物，即异佛司可林、去酰基佛司可林、1-乙酰基佛司可林，体外测定它们激动腺苷酸......
Exogenous cAMP upregulates the expression of glnII and glnK-amtB genes in Sinorhizobium meliloti 102
The existence of multiple adenylate cy- clase encoding genes implies the importance of cAMP in Sinorhizobium meliloti 10......
Oral submucous fibrosis(OSF) is a potentially malignant disorder that is characterized by a progressive fibrosis in the ......
蛛网膜下腔出血的病人有1/3以上,在出血后的某时间可发生脑血管痉挛,企图解除血管的痉挛至今仅取得极有限的成效。新近实验性工作......
Tetramethylpyrazine stimulates cystic fibrosis transmembrane conductance regulator-mediated anion se
AIM: To investigate the effect of tetramethylpyrazine (IMP), an active compound from Ligustium Wollichii Franchat, on el......
Interactions between neuronal and non-neuronal cells in adult rat isolated dorsal root ganglion cell
Objective The glial cells of the central nervous system are involved in tripartite signaling,therefore we have been inve......
Expression of pituitary adenylate cyclase-activating polypeptide 1 and 2 receptor mRNA in gallbladde
AIM: To detect the expression of pituitary adenylate cyclase-activating polypeptide receptor 1 (VPCAP1-R) and VPCAP2-R m......
Nitric oxide promotes survival of cerebellar granule neurons cultured in vitro through the Akt pathw
In this study,cerebellar granule neurons were used to examine the role of nitric oxide on cell survival.The N-methyl-D-a......
Chronic constipation is a common gastrointestinal disease severely affecting the patient’s quality of life. The traditi......
垂体腺苷酸环化酶激活肽(pituitary adenylate cyclase activating polypeptide,PACAP)是1989年发现的一种神经肽,已从下丘脑分离......
Targeting lysophospholipid signaling as a therapeutic approach towards improved peripheral nerve reg
Peripheral nerve injury causes a partial or total loss of motor and sensory functions as a result of axonal disruption a......
EFFECTS OF PARATHYROID HORMONE AND ESTRADIOL ON PROLIFERATION AND FUNCTION OF HUMAN OSTEOBLASTS FROM
The effect of parathyroid hormone (PTH) (0.01 nM-10 nM) and 17 -estradiol (E2, 1 nmol-10 nM) alone or in combination on ......
The mechanism of action of cadmium in the inductive pathway of metallothionein (MT) synthesis was studied in the rat. Ca......
Pharmacological evaluation of NSAID-induced gastropathy as a “Translatable” model of referred viscer
AIM To evaluate whether non-steroidal anti-inflammatory drugs(NSAIDs)-induced gastropathy is a clinically predictive mod......
小脑颗粒细胞是离体单细胞水平中枢神经元生物学研究的理想模型．随着细胞发育，其ＨＶＡ钙电流的基因表达、门控性质和药理学特征发生明显变......
In response to various neurohumoral substances en-dothelial cells release nitric oxide (NO) and prostacy-clin, and prod......
The cycle of G-protein activation and deactivation is a key in the signaling pathway of GPCRs (G protein coupled recept......
Aim:To investigate the effect of aluminum(Al)on high voltage-dependent cal-cium current(I_(HVA))and its modulation by g......
Sutherland和Rall等于1957～1958年在研究肾上腺素和高血糖素引起肝制备释放葡萄糖的作用原理中,首先发现环磷腺苷(cAMP),这些激素......
非洋地黄类正性肌力药近年来,非洋地黄类正性肌力药物发展迅速,为危重心功能衰竭(心衰)和难治性心衰病人的治疗开辟了一条新途径......
AIM: To investigate the muscarinic regulation of L-type calcium current (ICa_L) during development. METHODS: The whole c......
Intein-mediated Rapid Purification of Recombinant Human Pituitary Adenylate Cyclase Activating Polyp
In order to obtain the recombinant human PACAP efficiently by intein-mediated single column purification, a gene encodin......
INVOLVEMENT OF NITRIC OXIDE IN THE VASODILATOR AND DEPRESSOR EFFECT OF CALCITONIN GENE-RELATED PEPTI
In present study,we examined the effects of N~G-nitro-L-arginine(LNNA),an inhibitor of nitric oxide synthase(NOS),and/or......
研究可乐定（Ｃｌｏ）对大鼠烫伤后心脏β肾上腺素受体（βＡＲ）腺苷酸环化酶（ＡＣ）环腺苷一磷酸（ｃＡＭＰ）系统的作用．方法：大鼠于９５℃水浴中烫９ｓ，造成背部３０％皮肤全层......
Effect of Icariin on Cyclic GMP Levels and on the mRNA Expression of cGMP-binding cGMP-specific Phos
To further investigate the mechanisms of action of icariin (ICA), we assessed the effects of ICA on the in vitro formati......
EFFECT OF ANGIOTENSIN II RECEPTOR ANTAGONIST AND ENDOTHELIN RECEPTOR ANTAGONIST ON NITROGLYCERIN TOL
Objective. To investigate whether angiotensin II receptor antagonist and endothelin receptor antagonist can improve the ......
Down-regulation of C-type natriuretic peptide receptor by vasonatrin peptide in cardiac myocytes and
AIM: To investigate the regulatory effects of vasonatrin peptide (VNP) on the expression of C-type natriuretic peptide ......
AIM: To determine the effects of BN52021 on platelet-activating factor receptor (PAFR) signaling molecules under lipopol......
Aim:To obtain the recombinant,VPAC2-selective ( VPAC2:type 3 receptor ofpituitary adenylate cyclase activating polypept......
Shen-Fu Injection(参附注射液) Alleviates Post-resuscitation Myocardial Dysfunction by Up-regulating Expre
Objective: To compare the effect of Shen-Fu Injection(SFI) and epinephrine on the expression of sarcoplasmic reticulum C......
B族G蛋白偶联受体(G protein-coupled receptors,GPCRs)PAC1是垂体腺苷酸环化酶激活多肽(pituitary adenylate cyclase activating......
Plecanatide and dolcanatide, novel guanylate cyclase-C agonists, ameliorate gastrointestinal inflamm
AIM: To evaluate the effect of orally administeredplecanatide or dolcanatide, analogs of uroguanylin, on amelioration of......
Multistep hepatocarcinogenesis from a dysplastic nodule to well-differentiated hepatocellular carcin
We describe a rare case of the transformation of a dysplastic nodule into well-differentiated hepato- cellular carcinoma......
Purpose :To determine the effect of domestic Forskolin on lowering of intraocular pressure (IOP) in rabbits.Methods:Mea......
Laboratory testing and molecular analysis of the resistance of wild and cultivated soybeans to cotto
Identifying a superior soybean variety with high defoliator resistance is important to avoid yield loss. Cotton bollworm......
OBJECTIVE To study the role of I1-Imidazoline receptor(I1R) in opioid dependence.METHODS Subcellular location of μ opio......
Inhibition of phosphodiesterase 2 reverses behavioral and synaptic deficits caused by chronic stress
The major factors involved in the age-related neurodegenerative disease,such as progressive decline in cognitive functio......
