GSH相关论文
目的:研究麦冬乙醇提取物对肺腺癌A549细胞活性的影响及其作用机制。方法:实验选择人肺腺癌A549细胞株,给予不同浓度的麦冬乙醇提取物......
为探究还原型谷胱甘肽(reduced glutathione,GSH)对霞多丽葡萄酒酒精发酵结束后贮藏5个月期间理化指标、非挥发性代谢物和挥发性代谢......
肿瘤微环境与肿瘤的发展密切相关。复杂的肿瘤微环境不仅促进肿瘤的生长和转移,而且使肿瘤对多种治疗方式产生极强的治疗抵抗性。......
目的:探讨AMPK-PGC-1α信号通路及氧化应激在"上火"动物模型中的作用。方法:用干姜附子肉桂水煎液灌胃构建阴虚动物模型,用党参......
含硫小分子,如半胱氨酸(Cys),高半胱氨酸(Hcy),谷胱甘肽(GSH)和H2S等,参与生物体中许多重要的生理过程。其含量异常跟癌症密切相关,因此......
人胸腺素α1(Tα1)是由是人体中枢免疫器官胸腺组织上皮细胞所分泌的一种免疫活性极强的多肽激素,起着加强免疫系统功能的作用,可以......
目前,人们一般认为,葡萄糖在胚胎发育的早期起抑制作用,后期则起促进作用。但早期产生抑制作用的机理却没有定论。本实验以昆明小鼠的......
研究β-烟酰胺单核苷酸对衰老小鼠的抗氧化功能.衰老小鼠适应环境至少3d,按血清中丙二醛(MDA)水平分为7组,每组10只.各剂量组小鼠......
纳米技术的蓬勃发展使纳米传感器进入了新的篇章。因其荧光性能优异、发射峰窄而对称等优良的性质,半导体量子点(QDs)在分析检测领域......
背景与目的免疫球蛋白G4(Immunoglobulin G4,IgG4)是人类免疫球蛋白(Immunoglobulin G,IgG)中比较特殊的一个亚型,IgG4与IgG类型抗体可......
目的:探讨热量限制(CR)对老龄小鼠心肌铁死亡的保护作用及其与铁转运机制之间的关系。方法:选取24只不同月龄的健康雄性C57/BL6小鼠,......
以CdCl2·2.5H2 O为镉源,TeO2为碲源,水合肼为还原剂,利用共沉淀-还原法制备了CdTe纳米颗粒.采用扫描电镜、X射线衍射仪、激光拉曼......
A special o-dialdehyde fluorescent probe simultaneously sensing Hcy,GSH and its application in livin
The development of fluorescent probes enabling to distinguish Cys,Hcy and GSH has always been a con-siderable challenge,......
Advances in the controlled assembly of nanoscale building blocks have resulted in functional devices for nano-optoelectr......
Glutathione-Mediated Drug Release from Camptothecin-Conjugated Prodrug Nanomicelles Based on PEG-Pol
...
Hemichannels or gap junctions contributed to neuronal ischemic tolerance induced by astrocyte-condit
As a main subtype of gtia in the central nervous system, astrocytes have diverse and comprehensive functions, from nutri......
Objectives The purpose of this study is to investigate anti-oxidative effect of oral administration with JGT (Jeokbaekha......
目的 从细胞和分子水平探讨半胱胺(CS)对MPP+导致多巴胺能神经细胞毒性模型的保护作用;对其神经保护作用的机制进行实验观察与分析,......
Objective:To observe the clinical effects of cardioplegia with TAD in open heart surgery.Methods:In this study,30 patien......
谷胱甘肽(GSH),是由谷氨酸、半胱氨酸和甘氨酸组成的一种天然活性肽,存在于所有的动物细胞中,在基因表达调控、细胞保护、氨基酸转运......
[目的]观察孕哺期母鼠暴露2,4-二氯苯氧乙酸(2,4-dichlorophenoxyacetic acid,2,4-D)对仔代大鼠脑组织的脂质过氧化损伤作用及形态......
目的:初步探讨CpG ODN1826 对小鼠急性放射性肺损伤相关因子的作用及其可能的机制.方法:采用6 MVX 射线单次左肺照射20 Gy,建立小......
The anti-tumor activities of 0P46, a novel ent-kaurene diterpenoid compound from Isodonrubescens, an
Aim: This current study is designed to determine the cytotoxic effects of OP46, a new ent-kaurene diterpenoid isolated f......
Aging is a critical risk factor for Parkinsons disease.Silibinin,a major flavonoid in Silybum marianum,has been suggeste......
ONTD inhibits the growth of human hepatoma Bel-7402 cells via a MAPK dependent mitochondrial pathway
Background: ONTD, a novel synthetic triterpenoid from enoxolone, is a promising anticancer agent that has shown strong a......
为了降低毒性克服肿瘤多药耐药性以及增加阿霉素的生物药效,我们设计并研究了基于氧化还原敏感型的一种靶向修饰的五嵌段聚合物胶束......
药物和基因共递送在癌症治疗中的应用潜能逐渐彰显,但如何调控药物与基因的递送比例以及克服肿瘤多药耐药性,仍是当前面临的重要挑战......
对肿瘤细胞内GSH 的含量进行精准定量分析,能加深了解GSH 相关的化疗耐药机制。临床上急需一种无损、快速,并适用于活细胞内GSH 的实......
与天然过氧化物酶相比,人工过氧化物酶具有许多优点,例如:较宽范围的pH和温度响应,高的催化效率,低的合成和纯化成本,但是许多人工酶在水......
会议
生物硫醇包括半胱氨酸(Cys),高半胱氨酸(Hcy)和谷胱甘肽(GSH),然而细胞内的Cys 与Hcy 浓度较低,不足GSH 的10%.GSH 的浓度在1-10 mM 之......
Switching of DNA conformation by means of light as external stimulus has been a current research hotspot in the biologic......
Biothiols,including cysteine(Cys),homocysteine(Hcy),and glutathione(GSH),play crucial roles in many physiological proces......
会议
Advances in the controlled assembly of nanoscale building blocks have resulted in functional devices for nano-optoelectr......
微囊藻毒素MC-LR和MC-RR是中国蓝藻水华产生的中毒性最强、存在最普遍的种类,对鱼类、鸟类等水生动物以及家畜和野生动物都有毒害......
在兔胸腹部以胸腹壁静脉为轴形成4cm×6cm的静脉皮瓣。经静脉注射GSH,SOD,ATP-MgCl2,分别观察这三种药物对静脉皮瓣成活的影响。结果......
光活化农药是一种具有巨大开发潜力的新型绿色农药,但是其体外光不稳定性限制了它的应用。环境响应性聚合物纳米粒子作为农药传递......
Formyl tetrahydrofolate deformylase affects hydrogen peroxide accumulation and leaf senescence by re
It is well established that an abnormal tetrahydrofolate(THF)cycle causes the accumulation of hydrogen peroxide(H2O2)and......
目的 :探究在新生儿黄疸治疗中,将茵栀黄口服液与 GSH 联合应用的效果。方法 :于本院近半年收治的新生儿黄疸患儿中选取 62 例作为对......
Polybrominated diphenyl ethers(PBDEs),as one of the major persistence organic pollutants(POPs),have potential advers......
Effect of Fasudil Hydrochlorideand GSHand H2on the Post-Thaw Viabilityof Cryopreserved Porcine Adipo
Adipose-derived stem cells (ADSCs) are of interest for regenerative medicine as they are isolated easily and can dif......
目的:观察毫米波与γ线复合辐照对小鼠部分器MDA、GSH的含量和SOD活性的影响,探讨两种不同性质的电磁波产生生物效应的机理.方法:......
目的探讨营养支持联合丙氨酰谷氨酰胺治疗脓毒血症患者的临床疗效及对GSH、GIn等指标的影响作用。方法选取2018年1月至2020年1月我......
Glutathione (GSH), γ-Glu-Cys-Gly, is one of the most abundant small non-protein thiol molecules in mammalian tissues, p......
本文观察了24例糖尿病血小板还原型谷胱甘肽(GSH)浓度变化、血小板聚集及血浆ⅧR:Ag水平,并对血小板GSH含量与血小板聚集性之间的......
本文观察了29例原发性肾病综合征患儿血清 LPO,全血 GSH—PX、Se 活性改变,结果表明:血清 LPO 显著增高,全血 GSH—PX、Se 明显降......
目的:探讨外源性磷酸肌酸(PCr)在缺氧缺血性脑损伤中对线粒体功能的影响。方法:将96只七日龄Wistar新生鼠随机分为四组,分别为A假......
我们对喀喇昆仑山海拔5200m居住1年及其进驻前后的同一群体青年进行了血红蛋白(Hb),红细胞超氧化物歧化酶(RBC-SOD)和谷胱甘肽过氧化物......