MACROPHAGES相关论文
组织驻留巨噬细胞(tissue-resident macrophages,TRMs)是一类存在于人体绝大多数组织器官、独立于外周循环且具有一定自我更新能力的......
大量饮酒常会引起显著的肝脏损伤,包括肝脏炎症、纤维化、肝硬化,甚至肝癌.美他多辛被认为是治疗酒精性肝损伤(ALD)的有效药物,可......
Induction of multiple subroutines of regulated necrosis in murine macrophages by natural BH3-mimetic
Macrophages are critical sentinel cells armed with multiple regulated necrosis pathways,including pyroptosis,apoptosis f......
Inhibition of PDE4 by apremilast attenuates skin fibrosis through directly suppressing activation of
Systemic sclerosis(SSc)is a life-threatening chronic connective tissue disease with the characteristics of skin fibrosis......
系统性红斑狼疮(SLE)是一种以产生大量自身抗体为特征并累及多器官多系统的自身免疫性疾病。巨噬细胞的极化不平衡及异常活化与SLE的......
目的:评价鸢尾素对呼吸机相关性肺损伤(VILI)大鼠肺泡巨噬细胞极化的影响。方法:SPF级健康成年雄性SD大鼠30只,6~8周龄,体重200~250 ......
目的:基于弥漫大B细胞淋巴瘤(DLBCL)基因芯片表达数据库,分析肿瘤相关巨噬细胞及亚型浸润情况,探讨其与患者预后的相关性。方法:数据来......
目的:观察电针(EA)预处理对脂多糖(LPS)所致急性肺损伤(ALI)大鼠肺泡巨噬细胞(AMs)M1极化的影响,探讨EA保护ALI的可能机制.方法:将......
Changes and correlation of inflammatory polarization and Notch pathway in rats with adjuvant arthrit
Objective: To investigate the relationship between inflammatory polarization and Notch pathway in rats with adjuvant art......
目的:筛选支气管哮喘核心差异表达基因并对其进行生物信息学分析。方法:从基因表达数据库(GEO)下载哮喘患者巨噬细胞基因芯片数据GSE......
A novel tricyclic BTK inhibitor suppresses B cell responses and osteoclastic bone erosion in rheumat
Rheumatoid arthritis (RA) is characterized by joint leukocyte infiltration,synovial inflammation and bone damage result ......
C-X3-C motif chemokine ligand 1/receptor 1 regulates the M1 polarization and chemotaxis of macrophag
Background::Macrophages play an important role in renal ischemia reperfusion injury, but the functional changes of macro......
The phenotypic convergence between microglia and rperipheral macrophages during development and rneu
Microglia, the tissue resident macrophages of the brain, are increasingly recognized askey players for central nervous s......
Microglia-associated neuroinflammation plays an important role in the pathophysiology of ischemic stroke. Microglial act......
Quercetin modulates iron homeostasis and iNOS expression of splenic macrophages in a rat model of ir
Iron deficiency anemia is one of the most common micronutrient deficient conditions around the globe with various conseq......
Immunohistopathology of the contralateral testis of rats undergoing experimental torsion of the sper
Aim: To evaluate the immunohistopathological changes in the contralateral testis of rats after an experimental spermatic......
Androgen receptor deficiency in monocytes/macrophages does not alter adiposity or glucose homeostasi
Androgen deprivation in men leads to increased adiposity,but the mechanisms underlying androgen regulation of fat mass h......
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Grape-seed proanthocyanidins inhibit lipopolysaccharide-induced inflammatory mediators by suppressin
Proanthocyanindin extract is a mixture of polyphenols, mainly proanthocyanidins,obtained from grape seed with putative a......
Size-dependent cytotoxicity evaluation of DLC (diamond like carbon) wear debris in arthroplasty appl
Patients with DLC (diamond like carbon) coated artificial joint may be exposed to a wide size range of DLC wear debris (......
The lungs are the primary target organ of occupational, public and ambient exposure to (nano)particles (NP). Particulate......
Graphene oxide (GO) immunotoxicity is not clarified well up to date.Herein we reported the effects of GOs with and witho......
Macrophages,ubiquitous phagocytic cells in the human immune system,play a key role in homeostatic,immunological,and infl......
Effects of NMMA and catalase on intracellular survival of Vibrio alginolyticus in large yellow croak
The intracellular survival of Vibrio alginolyticus and V.parahaemolyticus in large yellow croaker macrophages was invest......
A Comparison of the Effects of Linear and Branched Polyethylenimine on Inflammatory Mechanisms in Mo
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Diamond like carbon(DLC)films are the most potential candidats of artificial joint in biomedical fields.In this study,we......
Comparison of Polysaccharides Contents and Invitro Immunological Activities of Fruit Bodies Among 10
The polysaccharides contents and immunological activities of fruit bodies from 10 different Hericium erinaceus stains we......
Screening key factor from sensory nerves regulating on macrophagein promoting bone defect healing an
To investigate the mechanism of bone defect healing is of great significance for taking corresponding measures to promot......
Objective In all the stages of atherogenesis,from lesion formation to plaque rupture,foamy macrophages which exhibit SR-......
A novel prognostic signature derived from a comprehensive characterization of the tumor microenviron
Objective Accumulating evidence has demonstrated that the tumor microenvironment(TME)is a crucial determinant of tumor g......
RegulatoryeffectsofmiR-155andmiR-146aonrepolarizationandinflammatorycytokinesecretionin
目的 WeplantodetectandseparatethephenotyeofAM(alveolarmacrophage)fromacuteandchronicMRSApneumonia patients,screenandveri......
NotchsignalingincrosstalkbetweenalveolarmacrophagesandTh17/Tregcellsinchronicobstructive
目的 Notchsignalingplayavitalroleincommunicationbetweeninnateimmunityandadaptiveimmunity.Here,weinvestigatedtheexpressio......
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MSC-conditioned medium alleviates acute liver injury and chronic liver fibrosis via acting on hepato
BACKGROUND: Liver is the most important metabolic organ for a majority of animals.Therefore, Liver failure,including acu......
Macrophages(Mφ)play a central role in the pathogenesis of rheumatoid arthritis(RA).The imbalance polarization may exist......
Stauntoside B derived from the roots of Cynanchum stauntonii possess anti-inflammatory activity thro
Background and Purpose: Stauntoside B was isolated from the root of Cynanchum stauntonii, a traditional Chinese medicine......
Background: TSP50 (Testes-specific protease 50) was abnormally overexpressed in many kinds of cancer tissues and it has ......
Background: Both acute liver injury and chronic liver fibrosis can lead to a potentially life-threatening condition, liv......
Backgroud and Purpose: Inflammation responses are involved in bacillus Calmette-Guerin (BCG) immunotherapy of Urothelial......
Deficiency of programmed cell death 4 attenuates atherosclerosis in hyperlipidemic mice through incr
Background: Programmed cell death 4 (PDCD4) is a newly defined transcriptional and translational inhibitor, and tumor su......
Tumor-infiltrating macrophages expressing interleukin-25 predict a favorable prognosis in gastric ca
Interleukin-25 (IL-25) is a newly described proinflammatory cytokine in the IL-17 family.The role of IL-25 during tumor ......
Effects and mechanisms of total glueosides of paeoniflorin derivatives (CP-25) on collagen-induced a
Aim: According to the changes that secondary paw swelling, polyarthritis index, and histological morphological of collag......
MicroRNA-124 feedback regulates TNF-a production via decreasing protein stability in LPS-triggered m
Aim: It was recently found miRNA-124, one of the most abundantly expressed miRNAs in the nervous system, could promotes ......
Migration Behavior of Endothelial Cells in 3D Biomaterials to Mimic the Repair of Blood Vessels in V
Cell migration plays a crucial role in a variety of physiological and pathological processes ranging from wound healing,......
Resolvin D1 programes inflammation resolution through enhancing dying cell clearance-induced TGF-β i
Experimental autoimmune neuritis (EAN) is the animal model of human acute inflammatory demyelinating polyradicu-loneurop......
Interleukin-12p35 Deletion Promotes CD4 T-Cell-Dependent Macrophage Differentiation and Enhances Ang
Objective Interleukin-12 is essential for the differentiation of na(i)ve T cells into interferon-γ-producing T cells, w......
Protective effects of PAMAM dendrimers on acute pancreatitis induced by caerulin in mice: role of ma
Polyamidoamine (PAMAM) dendrimers of generation 5 (G5) has been widely used as carriers to deliver the therapeutic and d......