MITOGEN-ACTIVATED相关论文
Ethanolic extract of Puhuang (Pollen Typhae) modulates lipopoly-saccharide-induced inflammatory resp
OBJECTIVE:To evaluate the immune modulatory response of Puhuang (Pollen Typhae),ethanolic ex-tract of dried pollens (TP-......
Effects of Dendrobium candidum polysaccharides on microRNA-125b and mitogen-activated protein kinase
Background:Diabetic cataract is a common complication and a lens disorder in diabetes.Moreover,Dendrobium officinale pol......
目的 研究力达霉素(lidamycin,LDM)联合硼替佐米(bortezomib,BZM)的抗骨髓瘤作用及对丝裂原活化蛋白激酶(Mitogen-activated prote......
,Atorvastatin attenuates IL-6 production partly via activating heme oxygenase-1 in LPS-stimulated RA
...
Effect of pre-electroacupuncture on p38 and c-Fos expression in the spinal dorsal horn of rats suffe
Background Acupuncture is an effective way to relieve pain, but the mechanism by which electroacupuncture (EA) decreases......
Effect of pre-electroacupuncture on p38 and c-Fos expression in the spinal dorsal horn of rats suffe
Background Acupuncture is an effective way to relieve pain, but the mechanism by which electroacupuncture (EA) decreases......
Objective:To investigate to the expression effect of hypoxia and hypoxia/reoxygenation on ROS,MAPKs and cell apoptosis i......
Schistosoma japonicum egg antigen up-regulates fibrogenesis and inhibits proliferation in primary he
AIM:To investigate the effects of different concentrations of Schistosoma japonicum(S.japonicum) egg antigen on fibrogen......
AIM: To investigate role of putative mitogen-activated protein kinase activator with WD40 repeats (MAWD)/ MAWD binding p......
目的:探究miR-433-3p对有丝分裂原活化蛋白激酶(MAPK8)的靶向调控作用及其对肝癌细胞MHCC97H增殖、凋亡和迁移的调控作用。方法:RT......
Antagonistic Effects of N-acetylcysteine on Mitogenactivated Protein Kinase Pathway Activation,Oxida
Objective To evaluate the antagonistic effects of N-acetylcysteine(NAC)on mitogen-activated protein kinases(MAPK)pathway......
H pylori stimulates proliferation of gastric cancer cells through activating mitogen-activated prote
瞄准:探索 H pylori 由引起胃的上皮细胞的激活的机制。方法:VacA (+) 和 CagA (+) 标准 H pylori 线 NCTC 11637 和人的胃的腺癌导......
AIM:To investigate lipopolysaccharide(LPS) related signal transduction in interstitial cells of Cajal(ICCs) from mouse s......
Evidence for a role of mitogen-activated protein kinases in the treatment of experimental acute panc
Acute pancreatitis(AP) is an inflammatory disease characterized by acute inflammation and necrosis of the pancreatic par......
AIM:To explore the role and mechanisms of extracellular signal-regulated protein kinase-mitogen-activated protein kinase......
Colorectal cancer(CRC)remains one of the most common malignancies in the world.Although surgical resection combined with......
阿尔茨海默病(Alzheimer's disease,AD)的病理特征之一是神经元内存在神经原纤维缠结(neurofibrillary tangles,NFTs),后者是由过度磷酸......
Helicobacter pylori promotes invasion and metastasis of gastric cancer by enhancing heparanase expre
AIM To detect the mechanisms of Helicobacter pylori(H.pylori)infection in the invasion and metastasis of gastric cancer(......
BACKGROUND The human microRNA 375(MIR375)is significantly downregulated in human colorectal cancer(CRC)and we have previ......
目的:检测丝裂原活化蛋白激酶相互作用激酶2(mitogen-activated protein kinase-interacting kinase-2,Mnk2)在食管鳞状细胞癌中的表......
线粒体融合蛋白2( Mfn2)是一种高度保守的跨膜GTP酶,由新鉴定的抑癌基因Mfn2编码,它的抗肿瘤作用跟丝裂原活化蛋白激酶( MAPK)信号通路有......
Objective: To study the relation between the cytoplasmic region of each subunit of leukemia inhibitory factor (LIF) rece......
...
JAK2 and MAPK pathways are involved in the inhibitory effect of berberine hydrochloride on gastric c
Acknowledgements This work was supported by Educational Commission of Shanghai of China (2012JW19); Key Research Innovatio......
目的探讨银杏叶提取物(Egb)761对血管性痴呆(VD)大鼠海马CAl区神经元凋亡及p38MAPK磷酸化表达的影响,并观察大鼠空间学习、记忆能力的变......
AIM:To identify novel substrates for the mitogen-activated protein kinase-activated protein kinase 5(MK5).METHODS:Yeast ......
Epidermal Growth Factor Enhances Orthovanadate-Induced Contraction via Src and Myosin Phosphatase Ta
Inhibition of protein tyrosine phosphatase by orthovanadate induces vasoconstriction, which is mediated by the Rho kinas......
12/15-Lipoxygenase inhibition counteracts MAPK phosphorylation in mouse and cell culture models of d
Background: Increased mitogen-activated protein kinase (MAPK) phosphorylation has been detected in peripheral nerve of h......
丝裂原活化蛋白激酶(MAPK)信号通路介导多种重要的细胞生理反应.对下游蛋白激酶的磷酸化是MAPK家族成员发挥生理作用的重要方式.在MAPK......
Synthetic lethal short hairpin RNA screening reveals that ring finger protein 183 confers resistance
Background: The mitogen-activated extracellular signal-regulated kinase 1/2 (MEK1/2) inhibitor trametinib has shown prom......
Effect of phosphorylation of MAPK and Stat3 and expression of c-fas and c-jun proteins on hepatocarc
AIM To study the effect of phosphorylation ofMAPK and Stat3 and the expression of c-fos andc-jun proteins on hepatocellu......
The mortality rate of gastric cancer worldwide is as high as 70%, despite the development of novel therapeutic strategie......
目的:探讨著蓣皂苷元(diosgenin,Dio)对人食管癌Eca109细胞的增殖、凋亡、迁移和侵袭的影响以及其作用机制.方法:MTT和Transwell实验检测......
AIM:To evaluate the current role of sorafenib,an oral multikinase inhibitor in the treatment of breast cancer.METHODS:An......
Objective:To study the relationship of high-risk human papilloma virus (HPV) infection with mitogen-activated protein ki......
Correlation of p38MAPK,ERK1/2 and JNK expression in peripheral blood with the cytokines and pain med
Objective: To study the correlation of p38MAPK, ERK1/2 and JNK expression in peripheral blood with the cytokines and pai......
The mechanisms underlying the secondary or delayed cell death in the hippocampus and cerebral hemisphere after traumatic......
Physiological roles of mitogen-activated-protein-kinase-activated p38-regulated/activated protein ki
Mitogen-activated protein kinases(MAPKs)are a family of proteins that constitute signaling pathways involved in processe......
Insulin induces PKC-dependent proliferation of mesenteric vascular smooth muscle cells from hyperten
Background and objectives Proliferation of human vascular smooth muscle cells (VSMCs) induced by hyperinsulinemia is a v......
The number of patients suffering from symptoms associated with gastrointestinal(GI) motility disorders is on the rise. G......
背景与问题 人血管eNOS不仅参与了血压调整、血管通透性调节、防止白细胞粘附和血小板聚集等生理过程,而且还涉及休克、高血压、动......