TNFΑ相关论文
乳腺癌是世界范围女性中最常见的一种恶性肿瘤。在我国,乳腺癌是女性发病率最高的恶性肿瘤,严重威胁着女性（尤其是年轻女性）的身体健......
目的:研究KA诱导BV2小胶质细胞激活,利用其诱导星形胶质细胞观察TNFα-TNFR1-NFκB在癫痫神经炎症反应中的作用。方法:采用KA诱导......
自噬是溶酶体依赖的细胞内成分降解的生物学过程,细胞通过自噬实现自我更新,维持重要的生命活动。脂肪组织调控糖脂代谢,在维持全......
软骨肉瘤是起源于骨组织的一种恶性肿瘤,是第二大常见的骨肿瘤,且对放化疗药物均不敏感。吡咯喹啉醌（PQQ）是一种可溶于水,并且具有较......
Heat stress can stimulate an increase in body temperature,which is correlated with increased expression of heat shock pr......
Introduction Adiponectin,a circulating cytokine exclusively secreted by adipocytes,plays its role via binding toits rece......
目的：本文主要研究早期股骨头坏死与骨关节炎患者滑膜中IL-23 的表达以及滑膜形态学的改变，明确IL-23在早期股骨头坏死中所起的作用，......
目的 构建重组腺病毒ad-siTNFα-BMP2双基因共表达在细胞水平的鉴定，为进一步的体内实验提供了实验基础. 方法 先构建腺病毒E3区表......
Deletion of Opg leads to increased neovascularization and expression of inflammatory cytokines in th
Introduction:Summary of Background Data.Osteoporosis is a controversial risk factor for IVD degeneration....
目的：明确低氧刺激对成骨细胞TNFα的影响并对其分子机制进行探索。方法：1％低氧刺激MC3T3E1,TRzol提取RNA,qRT-PCR测定细胞TNFα、COX......
研究目的：探讨肿瘤坏死因子-α(TNFα)通过上调口腔鳞癌细胞CAL27 中Krüppel 样因子4(KLF4)表达对细胞增 殖的影响. 研究方法：用不......
Impairment of inflammatory cytokine-induced manganese superoxide dismutase expression by the PINK1 G
Aim: Parkinsons disease is one of the most common neurodegenerative diseases.Mutation in human PTEN induced protein kina......
Objective: The pro-inflammatory cytokine tumor necrosis factor-alpha(TNFα)regulates synaptic scaling,which may be invol......
目的：探讨针刺百会穴对AD 模型鼠大脑皮质组织小胶质细胞分泌前炎症介质TNFα的影响。方法：Aβ1-42 侧脑室注射造AD 模型大鼠，针刺百......
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目的:研究大黄有效成分大黄酸抑制脂多糖(Lipopolysaccharide，LPS)刺激巨噬细胞释放肿瘤坏死因子(TNF?)作用的细胞信号通路。方法:......
Digitoflavone inhibits I κ B α kinase and enhances apoptosis induced by TNF α through downregulation
Tumor necrosis factor-α (TNFα) activates both cell death and cell survival pathways,thereby rendering most cancer cell......
目的 迄今TNFα-308G/A的多型变化与COPD的相关性研究往往结论不一.本研究通过构建更为严谨的入组标准及分析方案以明确两者关系.......
Down-regulation of progranulin improve learning and memory in a mice model of fragile x syndrome thr
Fragile X syndrome(FXS)is the most common inherited cause of autism and intellectual disability only after Downs syndrom......
Aim: To investigate the potential role of bone marrow stromal cells(BMSCs)in protecting neurons under the inflammatory c......
Objectives To elucidate the molecular mechanisms regarding the decreased glomerular filtration rate when hepatorenal syn......
体外培养人前体脂肪细胞,在诱导人前体脂肪细胞分化成熟的基础上,应用不同浓度(0ng/ml、5ng/ml、10ng/ml、25ng/ml、50ng/ml)人重......
本文探讨了鼻渊舒口服液对急性鼻窦炎大鼠鼻粘膜中TNFα的影响.方法:用不同剂量的鼻渊舒口服液治疗急性鼻窦炎大鼠,同时应用其他常......
目的：通过空中坠落性肝脏撞击伤后肝脏功能指标的检测,探讨该型肝脏损伤的早期敏感指标。方法：采用高空动物坠落撞击地面障碍物造成......
为了揭示2型糖尿病(NIDDM)合并急性脑梗死(ACI)细胞免疫系统与病程过程的关系,本文对肿瘤细胞坏死因子(TNFα)和白细胞介素6(IL-6)......
Tumor necrosis factor alpha (TNFα) induced mouse fibrosarcoma L929 cell necroptosis by inhibiting p3
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Establishment and Evaluation of a Transgenic Mouse Model of Arthritis Induced by Overexpressing Huma
Tumor necrosis factor alpha (TNFα) plays a key role in the pathogenesis of rheumatoid arthritis (RA).Blockade of TNFα ......
检测了甲、乙型病毒性肝炎患者外周血单个核细胞（PBMCs）IL-1、IL-6和TNFa的诱生活性及其血清中活性。结果表明，乙型慢性活动性肝炎（CAH......
肿瘤坏死因子α(TNFα)广泛表达于多种恶性肿瘤组织中,并与患者的恶性临床特征相关。作为一种重要的炎性因子,TNFα的作用与肿瘤发......
MicroRNA 是具有转录后调控功能的小分子非编码RNA,参与多种生理、病理过程。近年研究显示,体液中存在着大量游离于细胞之外的......
Cationic Peroxidase from Proso Millet Induces Human Colon Cancer Cell Necroptosis by Regulating Auto
Necroptosis is a caspase-independent form of regulated cell death executed by receptor interacting protein kinase 1(......
Evaluation of hGM-CSFhTNFαsurface-modified prostate cancer therapeutic vaccine in the hPBMC-SCID chi
Prostate cancer is currently the second leading cause of cancer-related death in elderly men. Prostate cancer likely......
目的: 检测人缺血脑组织中TNF-α和IL-1β的表达.方法: 将13例脑梗死的死亡病例按发病时间分成<2 d、 3～5 d、 >5 d 3个组, 以非缺......
目的：猪繁殖与呼吸综合征病毒(PRRSV)可引起以母猪繁殖障碍、仔猪呼吸困难为主要特征的高度传染病，给养猪业造成了巨大的经济损......
目的：研究肿瘤坏死因子α(TNF-α)诱导下,膀胱癌细胞中NF-κB通路分子的表达变化及其对细胞增殖水平的影响。方法：50 ng/ml TNF-......
目的:体外研究miR-203介导TNFα调控人牙周膜干细胞(human periodontal ligament stem cell, hPDLSCs)成骨分化能力及其分子机制。......
Signaling mechanisms in alcoholic liver injury: Role of transcription factors,kinases and heat shock
Alcoholic liver injury comprises of interactions of various intracellular signaling events in the liver. Innate immune r......
为了解在强制戒毒过程中，外周血自然杀伤细胞（ＮＫＣ）活性及单个核细胞分泌的ＩＬ－２ 活性变化，以及外周血清中ＩＬ－６ 及肿瘤坏死因子α（ＴＮＦα）水平的变化，对５１ 例......
乳腺癌是全世界女性发病率最高的癌症类型,是一种严重危害女性身心健康的恶性肿瘤。肿瘤干细胞也称作肿瘤起始细胞,是肿瘤内一群对......
【目的】核糖核酸(RNA)N6-甲基腺苷(N6-methyladenosine,m6A)修饰是一种动态可逆的过程,由甲基转移酶样蛋白3(methyltransferase l......
目的探讨小儿良、恶性实体瘤sIL-2R、TNFα的表达差异及其术后变化规律.方法选择30例恶性实体瘤、15例良性实体瘤和15例健康儿童,......
目的 探讨谷红注射液(金特佳)对急性脑梗死(ACI)患者血清IL-6、TNFα的影响及临床意义.方法 选择63例发病＜24 h的颈内动脉系统ACI患......
目的探讨重症胰腺炎感染期TNFα的变化特点与器官功能的关系.方法测定21例感染期病人的血、尿、胆汁和正常人血清、胆汁内TNFα活......
