子宫肌瘤(Uterine fibroids,UF)是女性常见的生殖系统良性肿瘤,其治疗方式有手术治疗、药物治疗及微创治疗。其中高强度聚焦超声(high intensity focused ultrasound,HIFU)是近年发展起来的非侵入性局部高温治疗肿瘤的新微创治疗技术,HIFU作为一种非侵入性、安全有效的无创治疗方式,因其可以保留子宫结构及功能、不影响卵巢内分泌及生殖功能的优势,广泛应用于子宫肌瘤的治疗,并取得了一定的成果;同时受到临床妇科医生的关注。探索新的无创局部治疗方法是近年来国内外学者关注的问题。本文将HIFU在治疗子宫肌瘤的临床研究作一综述。 Uterine fibroids (UF) are common benign tumors of the reproductive system in women. They are treated by surgical treatment, medical treatment and minimally invasive treatment. Among them, high intensity focused ultrasound (HIFU) is a new minimally invasive treatment of non-invasive hyperthermic tumors developed in recent years. HIFU, as a noninvasive, safe and effective non-invasive treatment, Retained uterine structure and function, does not affect the ovarian endocrine and reproductive function advantages, widely used in the treatment of uterine fibroids, and achieved some results; at the same time by the concern of clinical gynecologists. In recent years, exploring new non-invasive local treatment methods has attracted the attention of scholars at home and abroad. This article will HIFU in the treatment of uterine fibroids clinical research is reviewed.