自1975年杂交瘤技术问世以来,单克隆抗体(单抗)在肿瘤学领域得到了广泛的研究和应用。1979年Huberman等首先制备出抗人肺癌的单抗,短短几年中,单抗在肺癌方面的研究有了长足的发展。本文试对近年来单抗在肺癌诊断和治疗中的应用及前景作一概述。 Since the advent of hybridoma technology in 1975, monoclonal antibodies (monoclonal antibodies) have been extensively studied and applied in the field of oncology. In 1979, Huberman et al. first prepared anti-human lung cancer monoclonal antibody. In a few short years, the research of monoclonal antibody in lung cancer has made considerable progress. This article tries to give an overview of the application and prospects of monoclonal antibodies in the diagnosis and treatment of lung cancer in recent years.