本文报道4例恶性黑色素瘤,其中3例为甲下肢端雀斑样黑色素瘤,1例为无色素性黑色素瘤。在光镜观察基础上做了电镜观察。黑素小体一般为0.5～0.8μ,并有巨大黑素小体(1.06×0.7μ)、黑素小体复合体;例2在细胞内发现二个病毒样颗粒呈同心圆形,例4为无色素性恶性黑色素瘤(AMM),于细胞内发现较小的黑素小体,数量亦少。 This article reports 4 cases of malignant melanoma, of which 3 cases of a lower extremity freckled melanoma, 1 case of non-pigmented melanoma. The electron microscope observation was made on the basis of light microscope observation. Melanoid bodies are generally 0.5 ~ 0.8μ, and have a large melanin body (1.06 × 0.7μ), melanin body complex; Example 2 found in the cell two virus-like particles were concentric circular, Example 4 For non-pigmented malignant melanoma (AMM), smaller melanocytes were found in cells and the number was small.