恶性淋巴瘤是原发于淋巴系统的一组不同病理类型和不同临床行为的肿瘤,各型具有各自特征性的分子生物学改变。大量研究表明6q变异是淋巴瘤中常见的染色体异常,其最早在急性淋巴母细胞白血病中被发现。近年来通过多种新技术的应用,6q缺失的检出率增高,而且断裂点的定位也越来也? Malignant lymphoma is a group of tumors of different pathological types and different clinical behaviors originating in the lymphatic system. Each type has its own characteristic molecular biology changes. A large number of studies have shown that the 6q mutation is a common chromosomal abnormality in lymphoma, which was first discovered in acute lymphoblastic leukemia. In recent years, through the application of a variety of new technologies, the detection rate of 6q deletion has increased, and the location of breakpoints has also become more and more.