【摘 要】
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Approximately one person in 1,000 is a Robertsonian translocation carrier.This type of translocation most likely arises during egg (or more rarely sperm) formation.Most Robertsonian translocation carr
【机 构】
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Genetics Laboratory, Hubei Maternal and Child Health Hospital, Wuhan, Hubei, PR China
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Approximately one person in 1,000 is a Robertsonian translocation carrier.This type of translocation most likely arises during egg (or more rarely sperm) formation.Most Robertsonian translocation carriers are healthy and have a normal lifespan, but do have an increased risk of pregnancy loss and children with trisomies.We have found a Robertsonian translocation family, one of them who came from a consanguinous marriage has the previously undescribed balanced human karyotype 44,XY, der(14;15)(q10;q10), der(14;15)(q10;q10).Many such rearrangements in natural populations of different species are known.It is well-known that the fitness of rob translocation carries is reduced, but rob translocation can provide material for evolution.
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