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为了探讨36例封闭抗体不足习惯性流产患者接受淋巴细胞免疫治疗的效果。病例选自2007年1月至2009年12月在三家医院就诊36例封闭抗体阴性习惯性流产患者,进行淋巴细胞免疫治疗。结果显示:36例患者在接受3个疗程的免疫治疗后,封闭抗体转为阳性30例(83.3%),与治疗前比较有统计学意义(P<0.01)。32例再次妊娠,3例再次发生早中期流产,妊娠时间维持到28~32周者共2例,32周~36+6周21例,足月分娩活婴6例,妊娠总成功率为80.6%。结果表明,淋巴细胞免疫是一种治疗封闭抗体不足习惯性流产有效、安全的方法。
In order to investigate the effect of 36 cases of HBeAg-deficient habitual abortion receiving lymphocyte immunotherapy. Cases from January 2007 to December 2009 in three hospitals for 36 cases of closed antibody negative habitual abortion in patients with lymphocyte immunotherapy. The results showed that after receiving three courses of immunotherapy in 36 patients, the blocking antibodies turned positive in 30 cases (83.3%), which was statistically significant compared with that before treatment (P <0.01). 32 cases of pregnancy again, 3 cases of early miscarriage again, pregnancy time to 28 to 32 weeks were 2 cases, 32 weeks to 36 + 6 weeks in 21 cases, full-term delivery of live infants in 6 cases, pregnancy total success rate of 80.6 %. The results show that lymphocyte immunity is an effective and safe method to treat habitual abortion with insufficient blocking antibody.