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[目的]观察雾化吸入长效受体激动剂及糖皮质激素治疗慢性阻塞性肺疾病急性加重期(AECOPD)的效果。[方法]106例AECOPD住院患者,随机分2组,对照组53例给予常规治疗,治疗组53例给予常规治疗的同时,吸入沙美特罗50μg及丙酸氟替卡松。分析治疗后患者临床呼吸困难症状改善、肺部罗音的吸收和住院天数的变化。[结果]治疗组呼吸困难症状明显改善,肺功能明显改善,肺部罗音明显吸收,住院天数明显缩短,与对照组差异均有统计学意义(P﹤0.05,P﹤0.01)。[结论]长效受体激动剂及糖皮质激素雾化吸入对AECOPD疗效肯定,并且副作用小,可作为治疗AECOPD的有效方案。
[Objective] To observe the effect of aerosol inhaled long-acting receptor agonist and glucocorticoid on acute exacerbation of chronic obstructive pulmonary disease (AECOPD). [Methods] One hundred and sixty AECOPD inpatients were randomly divided into two groups. The control group received routine therapy. In the treatment group, 53 patients were given routine treatment while 50 μg salmeterol and fluticasone propionate were inhaled. Analysis of clinical symptoms of patients with dyspnea after treatment to improve the absorption of lung rales and changes in hospital days. [Results] The symptoms of dyspnea in the treatment group were significantly improved, the lung function was obviously improved, the pulmonary rales were obviously absorbed and the days of hospitalization were significantly shortened, which were significantly different from the control group (P <0.05, P <0.01). [Conclusion] Long-acting receptor agonist and inhalation of glucocorticosteroid have a positive curative effect on AECOPD and little side effect, which can be used as an effective treatment for AECOPD.