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[目的]观察丹红注射液联合西药治疗慢性阻塞性肺疾病急性加重期疗效。[方法]使用随机平行对照方法,将128例住院患者按掷骰子法随机分为两组。对照组64例常规治疗,祛痰、平喘、解痉、抗感染、纠正水电解质失衡。治疗组64例40mL丹红注射液+250mL0.9%生理盐水(或5%葡萄糖溶液),1次/d,静滴。西药治疗同对照组。连续治疗14d为1疗程。观测临床症状、不良反应。治疗1疗程,判定疗效。[结果]治疗组显效55例,有效8例,无效1例,总有效率98.88%。对照组显效39例,有效16例,无效9例,总有效率85.94%。治疗组疗效优于对照组(P<0.05)。血液流变学指标两组均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。[结论]丹红注射液联合西药治疗慢性阻塞性肺疾病急性加重期效果显著,值得推广。
[Objective] To observe the effect of Danhong injection combined with western medicine in treating acute exacerbation of chronic obstructive pulmonary disease. [Methods] Using randomized parallel control method, 128 inpatients were randomly divided into two groups according to the dice method. Control group, 64 cases of conventional treatment, expectorant, asthma, antispasmodic, anti-infective, correct water and electrolyte imbalance. Treatment group, 64 cases of 40mL Danhong injection + 250mL0.9% saline (or 5% glucose solution), 1 / d, intravenous infusion. Western medicine treatment with the control group. Continuous treatment 14d for a course of treatment. Observed clinical symptoms, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Results] The treatment group markedly effective in 55 cases, effective in 8 cases, 1 case, the total effective rate was 98.88%. In the control group, 39 cases were markedly effective, 16 cases were effective, 9 cases were ineffective, and the total effective rate was 85.94%. The treatment group was better than the control group (P <0.05). The indexes of hemorheology were improved in both groups (P <0.05), and the improvement in the treatment group was better than that in the control group (P <0.05). [Conclusion] Danhong injection combined with Western medicine has a significant effect in treating acute exacerbation of chronic obstructive pulmonary disease and is worth promoting.