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变应性鼻炎鼻黏膜组织中嗜酸粒细胞(eosinophil,EOS)的浸润与症状的严重程度密切相关[1,2],但有关EOS在鼻黏膜中持续增多的机制尚未完全阐明,但有学者认为变应性鼻炎和骨髓间可能存在一种反馈机制[3]。已知有多种细胞因子参与了EOS的生成和趋化,其中以白细胞介素5(interleukin5
The infiltration of eosinophils (EOS) in nasal mucosa of allergic rhinitis is closely related to the severity of the symptoms [1,2]. However, the mechanism of continuous increase of EOS in the nasal mucosa has not yet been fully elucidated, but some scholars That allergic rhinitis and bone marrow may exist a feedback mechanism [3]. A variety of cytokines are known to be involved in the generation and chemotaxis of EOS, among which interleukin 5